Active Not Recruiting PHASE3 INTERVENTIONAL 1-arm NCT03424018

An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia

A Phase 3, Open-Label Long-Term Extension Study to Evaluate the Safety and Efficacy of BMN 111 in Children With Achondroplasia

Sponsor: BioMarin Pharmaceutical

Conditions Achondroplasia

Interventions BMN 111

Updated 22 times since 2018 Last updated: Mar 12, 2026 Started: Dec 12, 2017 Primary completion: Jun 30, 2031 Completion: Jun 30, 2031

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Achondroplasia, this trial is ongoing. The trial is conducted by BioMarin Pharmaceutical and has accumulated 22 data snapshots since 2017. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

22 versions recorded

Mar 2026 — Present [monthly]

Active Not Recruiting PHASE3
Sep 2025 — Mar 2026 [monthly]

Active Not Recruiting PHASE3
Feb 2025 — Sep 2025 [monthly]

Active Not Recruiting PHASE3
Nov 2024 — Feb 2025 [monthly]

Active Not Recruiting PHASE3
Sep 2024 — Nov 2024 [monthly]

Active Not Recruiting PHASE3

▶ Show 17 earlier versions

Jul 2024 — Sep 2024 [monthly]

Active Not Recruiting PHASE3
Jan 2024 — Jul 2024 [monthly]

Active Not Recruiting PHASE3
Jul 2023 — Jan 2024 [monthly]

Active Not Recruiting PHASE3
Jan 2023 — Jul 2023 [monthly]

Active Not Recruiting PHASE3
Sep 2022 — Jan 2023 [monthly]

Active Not Recruiting PHASE3
May 2022 — Sep 2022 [monthly]

Active Not Recruiting PHASE3
Sep 2021 — May 2022 [monthly]

Active Not Recruiting PHASE3
Feb 2021 — Sep 2021 [monthly]

Active Not Recruiting PHASE3
Jan 2021 — Feb 2021 [monthly]

Active Not Recruiting PHASE3
Aug 2020 — Jan 2021 [monthly]

Active Not Recruiting PHASE3
Feb 2020 — Aug 2020 [monthly]

Active Not Recruiting PHASE3
Jan 2020 — Feb 2020 [monthly]

Active Not Recruiting PHASE3

Status: Enrolling By Invitation → Active Not Recruiting
Nov 2019 — Jan 2020 [monthly]

Enrolling By Invitation PHASE3
Jun 2019 — Nov 2019 [monthly]

Enrolling By Invitation PHASE3
Aug 2018 — Jun 2019 [monthly]

Enrolling By Invitation PHASE3
Jun 2018 — Aug 2018 [monthly]

Enrolling By Invitation PHASE3
Mar 2018 — Jun 2018 [monthly]

Enrolling By Invitation PHASE3

First recorded

Dec 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

BioMarin Pharmaceutical

Data source: BioMarin Pharmaceutical

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Baltimore, United States , Barcelona, Spain , Chicago, United States , Cincinnati, United States , Columbia, United States , Houston, United States , Istanbul, Turkey (Türkiye) , London, United Kingdom , Magdeburg, Germany and 13 more locations