deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 4-arm NCT03451851

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants (PROTOSTAR)

A Phase 3, Multicenter, Randomized, Placebo- and Active Comparator-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Subjects (>=6 To <18 Years of Age)

Sponsor: Janssen Research & Development, LLC

Conditions Psoriasis
Updated 82 times since 2018 Last updated: Mar 11, 2026 Started: Jul 11, 2018 Primary completion: Jul 19, 2023 Completion: Dec 18, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Psoriasis and is currently ongoing. Janssen Research & Development, LLC leads this study, which shows 82 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~May 2018 · 30 days · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Jun 2020 · 3 months · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – present · 5 months · monthly snapshot

Change History

82 versions recorded
  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Feb 2026 — Mar 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Jan 2026 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  4. Dec 2025 — Jan 2026 [monthly]

    Active Not Recruiting PHASE3

  5. Nov 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE3

Show 77 earlier versions
  1. Oct 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE3

  2. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jun 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE3

  5. May 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE3

  6. Apr 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  7. Feb 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE3

  8. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE3

  9. Nov 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE3

  10. Oct 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE3

  11. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE3

  12. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  13. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE3

  14. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  15. May 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE3

  16. Apr 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE3

  17. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE3

  18. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

  19. Jan 2024 — Feb 2024 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  20. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE3

  21. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE3

  22. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE3

  23. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE3

  24. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE3

  25. Jun 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  26. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE3

  27. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE3

  28. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

  29. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

  30. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE3

  31. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  32. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  33. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  34. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  35. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  36. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE3

  37. Mar 2022 — May 2022 [monthly]

    Recruiting PHASE3

  38. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE3

  39. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  40. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  41. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  42. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  43. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  44. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  45. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

  46. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  47. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  48. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  49. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  50. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  51. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  52. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  53. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

    Status: SuspendedRecruiting

  54. Jun 2020 — Jul 2020 [monthly]

    Suspended PHASE3

    Status: RecruitingSuspended

  55. Mar 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  56. Jan 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  57. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  58. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  59. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  60. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  61. Jul 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  62. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  63. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  64. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  65. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  66. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

  67. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE3

  68. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE3

  69. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE3

  70. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE3

  71. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  72. Aug 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE3

  73. Jul 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE3

  74. Jun 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE3

  75. May 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE3

  76. Apr 2018 — May 2018 [monthly]

    Not Yet Recruiting PHASE3

  77. Mar 2018 — Apr 2018 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Janssen Research & Development, LLC
Data source: Janssen Research & Development, LLC

For direct contact, visit the study record on ClinicalTrials.gov .