deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 2-arm NCT03452579

Nivolumab Plus Standard Dose Bevacizumab Versus Nivolumab Plus Low Dose Bevacizumab in GBM

CA209-382 A Randomized Phase 2 Open Label Study of Nivolumab Plus Standard Dose Bevacizumab Versus Nivolumab Plus Low Dose Bevacizumab in Recurrent Glioblastoma (GBM)

Sponsor: David Peereboom

Conditions Glioblastoma
Updated 13 times since 2018 Last updated: Feb 14, 2025 Started: May 21, 2018 Primary completion: Dec 30, 2020 Completion: Jun 30, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03452579, this PHASE2 trial focuses on Glioblastoma and remains ongoing. Sponsored by David Peereboom, it has been updated 13 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~Jul 2019 · 5 months · monthly snapshot~Jul 2019 – ~Feb 2020 · 7 months · monthly snapshot~Feb 2020 – ~Aug 2020 · 6 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jun 2021 · 4 months · monthly snapshot~Jun 2021 – ~Jul 2024 · 37 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – present · 14 months · monthly snapshot

Change History

13 versions recorded
  1. Mar 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Feb 2025 — Mar 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jun 2021 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

Show 8 earlier versions
  1. Feb 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  2. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE2

  3. Aug 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  4. Feb 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  5. Jul 2019 — Feb 2020 [monthly]

    Recruiting PHASE2

  6. Feb 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  7. Jun 2018 — Feb 2019 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  8. Mar 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • David Peereboom
Data source: Case Comprehensive Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .