deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT03464916

Study to Evaluate the Safety and Efficacy of Anti-CD38 CAR-T in Relapsed or Refractory Multiple Myeloma Patients

A Phase 1, Open-Label, Dose-Escalation, Pharmacokinetic, and Pharmacodynamic Study of the Safety and Efficacy of CAR2 Anti-CD38 A2 CAR-T Cells in Patients With Relapsed or Refractory Multiple Myeloma

Sponsor: Sorrento Therapeutics, Inc.

Updated 13 times since 2018 Last updated: Mar 14, 2022 Started: Oct 15, 2018 Primary completion: Aug 23, 2020 Completion: Feb 28, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Relapsed or Refractory Multiple Myeloma and is currently completed. Sorrento Therapeutics, Inc. leads this study, which shows 13 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Mar 2018 – ~May 2018 · 2 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~May 2019 · 10 months · monthly snapshot~May 2019 – ~Nov 2019 · 6 months · monthly snapshot~Nov 2019 – ~Aug 2020 · 9 months · monthly snapshot~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Apr 2022 · 12 months · monthly snapshot~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Apr 2022 — Jul 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  4. Apr 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  5. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE1

Show 8 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  2. Aug 2020 — Nov 2020 [monthly]

    Recruiting PHASE1

  3. Nov 2019 — Aug 2020 [monthly]

    Recruiting PHASE1

  4. May 2019 — Nov 2019 [monthly]

    Recruiting PHASE1

  5. Jul 2018 — May 2019 [monthly]

    Recruiting PHASE1

  6. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE1

  7. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  8. Mar 2018 — May 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Sorrento Therapeutics, Inc.
Data source: Sorrento Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .