deltatrials
Completed PHASE2/PHASE3 INTERVENTIONAL 3-arm NCT03485417

Substance Misuse To Psychosis for Stimulants

Substance Misuse To Psychosis for Stimulants (SToP-S)--An Early Assertive Pharmacotherapy Intervention Study

Sponsor: North District Hospital

Conditions Pharmacotherapy Schizophrenia and Related Disorders Stimulant Abuse Stimulant Dependence Stimulant Use With Stimulant-Induced Psychotic Disorder (Diagnosis)
Interventions Aripiprazole Paliperidone Treatment as Usual
Updated 17 times since 2018 Last updated: Nov 12, 2025 Started: Jun 1, 2019 Primary completion: May 31, 2024 Completion: May 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03485417, this PHASE2/PHASE3 trial focuses on Pharmacotherapy and Schizophrenia and Related Disorders and remains completed. Sponsored by North District Hospital, it has been updated 17 times since 2019, reflecting substantial change activity. Mental health research at this phase helps define safety and dosing parameters for future study.

Status Flow

~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Oct 2018 · 2 months · monthly snapshot~Oct 2018 – ~Mar 2019 · 5 months · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jul 2019 · 2 months · monthly snapshot~Jul 2019 – ~Aug 2020 · 13 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Aug 2023 · 11 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshot~Aug 2025 – ~Dec 2025 · 4 months · monthly snapshot~Dec 2025 – present · 8 months · monthly snapshot

Change History

17 versions recorded

  1. Dec 2025 — Present [monthly]

    Completed PHASE2/PHASE3

  2. Aug 2025 — Dec 2025 [monthly]

    Completed PHASE2/PHASE3

    Status: Recruiting → Completed

  3. Sep 2024 — Aug 2025 [monthly]

    Recruiting PHASE2/PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2/PHASE3

    Phase: PHASE2_PHASE3 → PHASE2/PHASE3

  5. Aug 2023 — Jul 2024 [monthly]

    Recruiting PHASE2_PHASE3

▶ Show 12 earlier versions

  1. Sep 2022 — Aug 2023 [monthly]

    Recruiting PHASE2_PHASE3

  2. Sep 2021 — Sep 2022 [monthly]

    Recruiting PHASE2_PHASE3

  3. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE2_PHASE3

  4. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE2_PHASE3

  5. Jul 2019 — Aug 2020 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Not Yet Recruiting → Recruiting

  6. May 2019 — Jul 2019 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  7. Apr 2019 — May 2019 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  8. Mar 2019 — Apr 2019 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  9. Oct 2018 — Mar 2019 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  10. Aug 2018 — Oct 2018 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  11. Jun 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  12. May 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • North District Hospital
  • Queen Mary Hospital, Hong Kong
  • The University of Hong Kong
Data source: The University of Hong Kong

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations