deltatrials
Unknown PHASE1 INTERVENTIONAL 2-arm NCT03491631

Phase I Study of SHR9146 + SHR-1210 +/- Apatinib in Patients With Advanced Solid Tumors

A Phase I Study to Characterize the Tolerance, Safety, Pharmacokinetics/Pharmacodynamics and Effect of PD-1 Inhibitor SHR-1210 in Combination With IDO Inhibitor SHR9146 and With/Without Apatinib in Patients With Advanced Solid Tumors (PIANO)

Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Updated 8 times since 2018 Last updated: Nov 1, 2022 Started: Nov 20, 2018 Primary completion: Jun 30, 2023 Completion: Sep 30, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Cancer, Metastatic and Neoplasm Malignant and is currently ongoing. Jiangsu HengRui Medicine Co., Ltd. leads this study, which shows 8 recorded versions since 2018 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~May 2018 – ~Jul 2018 · 2 months · monthly snapshotNot Yet Recruiting~Jul 2018 – ~Jul 2020 · 24 months · monthly snapshotNot Yet Recruiting~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshotUnknown Status~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshotUnknown Status~Dec 2022 – ~Jul 2024 · 19 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotActive Not Recruiting~Dec 2024 – present · 20 months · monthly snapshotUnknown

Change History

8 versions recorded
  1. Dec 2024 — Present [monthly]

    Unknown PHASE1

    Status: Active Not RecruitingUnknown

  2. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Dec 2022 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: Unknown StatusActive Not Recruiting

  5. Jan 2021 — Dec 2022 [monthly]

    Unknown Status PHASE1

Show 3 earlier versions
  1. Jul 2020 — Jan 2021 [monthly]

    Unknown Status PHASE1

    Status: Not Yet RecruitingUnknown Status

  2. Jul 2018 — Jul 2020 [monthly]

    Not Yet Recruiting PHASE1

  3. May 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Jiangsu HengRui Medicine Co., Ltd.
Data source: Jiangsu HengRui Medicine Co., Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations