deltatrials
Completed PHASE1 INTERVENTIONAL 9-arm NCT03502330

APX005M With Nivolumab and Cabiralizumab in Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma

A Phase I/Ib Study of APX005M in Combination With Nivolumab and Cabiralizumab in Patients With Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma Whose Disease Has Progressed on Anti-PD- 1/PD-L1 Therapy

Sponsor: Apexigen America, Inc.

Updated 14 times since 2018 Last updated: Jun 21, 2024 Started: Jun 9, 2018 Primary completion: Jan 5, 2022 Completion: May 15, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Advanced Melanoma and Non-small Cell Lung Cancer, this trial is completed. The trial is conducted by Apexigen America, Inc. and has accumulated 14 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2019 · 13 months · monthly snapshot~Aug 2019 – ~Oct 2019 · 2 months · monthly snapshot~Oct 2019 – ~Jan 2021 · 15 months · monthly snapshot~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshot~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshot~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  3. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Jun 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE1

Show 9 earlier versions
  1. Mar 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Mar 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  4. Jan 2021 — Mar 2022 [monthly]

    Recruiting PHASE1

  5. Oct 2019 — Jan 2021 [monthly]

    Recruiting PHASE1

  6. Aug 2019 — Oct 2019 [monthly]

    Recruiting PHASE1

  7. Jul 2018 — Aug 2019 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  8. Jun 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE1

  9. May 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Apexigen America, Inc.
  • Bristol-Myers Squibb
  • National Cancer Institute (NCI)
  • Yale University
Data source: Yale University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations