deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03504241

Tolerance by Engaging Antigen During Cellular Homeostasis (TEACH)

Donor-derived Mesenchymal Stromal Cells, Alemtuzumab, Co-stimulation Blockade and Sirolimus for Tolerance Induction in Adult Kidney Allograft Recipients (ITN062ST)

Sponsor: Immune Tolerance Network (ITN)

Updated 19 times since 2018 Last updated: Feb 10, 2026 Started: Jul 30, 2018 Primary completion: Sep 6, 2023 Completion: Sep 16, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Kidney Transplantation and Renal Transplant Recipient, this trial is completed. The trial is conducted by Immune Tolerance Network (ITN) and has accumulated 19 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~May 2019 · 9 months · monthly snapshot~May 2019 – ~Apr 2020 · 11 months · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshot~Jun 2021 – ~Jun 2022 · 12 months · monthly snapshot~Jun 2022 – ~Feb 2023 · 8 months · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Feb 2024 · 11 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Mar 2025 · 5 months · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshot~Jun 2025 – ~Feb 2026 · 8 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

19 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  2. Jun 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Mar 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Oct 2024 — Mar 2025 [monthly]

    Active Not Recruiting PHASE1

  5. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE1

Show 14 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  2. Feb 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

  3. Mar 2023 — Feb 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Feb 2023 — Mar 2023 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  5. Jun 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  6. Jun 2021 — Jun 2022 [monthly]

    Recruiting PHASE1

  7. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE1

  8. May 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  9. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE1

  10. May 2019 — Apr 2020 [monthly]

    Recruiting PHASE1

  11. Aug 2018 — May 2019 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  12. Jul 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE1

  13. Jun 2018 — Jul 2018 [monthly]

    Not Yet Recruiting PHASE1

  14. May 2018 — Jun 2018 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Immune Tolerance Network (ITN)
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • PPD Development, LP
  • Rho Federal Systems Division, Inc.
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations