deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT03511963

A Clinical Study to Compare the Efficacy, Safety and Immunogenicity of HLX04 and Bevacizumab Combined XELOX or mFOLFOX6 in the First-line Treatment of mCRC

A Randomized, Double-blind, Parallel Control, Multicenter, Phase III Clinical Study to Compare the Efficacy and to Evaluate the Safety and Immunogenicity of HLX04 and Bevacizumab Combined With Oxaliplatin and Fluoropyrimidine-based Chemotherapy (XELOX or mFOLFOX6) in the First-line Treatment of Metastatic Colorectal Cancer (mCRC)

Sponsor: Shanghai Henlius Biotech

Updated 10 times since 2018 Last updated: Dec 29, 2024 Started: Apr 9, 2018 Primary completion: Apr 15, 2020 Completion: Apr 20, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Metastatic Colorectal Cancer (mCRC), this trial is completed. The trial is conducted by Shanghai Henlius Biotech and has accumulated 10 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~May 2018 – ~Jun 2018 · 31 days · monthly snapshotRecruiting~Jun 2018 – ~Jun 2020 · 24 months · monthly snapshotRecruiting~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotUnknown Status~Jan 2021 – ~Feb 2022 · 13 months · monthly snapshotActive Not Recruiting~Feb 2022 – ~Jun 2022 · 4 months · monthly snapshotActive Not Recruiting~Jun 2022 – ~Jun 2024 · 24 months · monthly snapshotActive Not Recruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotUnknown~Feb 2025 – present · 17 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Feb 2025 — Present [monthly]

    Completed PHASE3

    Status: UnknownCompleted

  2. Sep 2024 — Feb 2025 [monthly]

    Unknown PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE3

    Status: Unknown StatusUnknown

  4. Jun 2024 — Jul 2024 [monthly]

    Unknown Status PHASE3

    Status: Active Not RecruitingUnknown Status

  5. Jun 2022 — Jun 2024 [monthly]

    Active Not Recruiting PHASE3

Show 5 earlier versions
  1. Feb 2022 — Jun 2022 [monthly]

    Active Not Recruiting PHASE3

  2. Jan 2021 — Feb 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: Unknown StatusActive Not Recruiting

  3. Jun 2020 — Jan 2021 [monthly]

    Unknown Status PHASE3

    Status: RecruitingUnknown Status

  4. Jun 2018 — Jun 2020 [monthly]

    Recruiting PHASE3

  5. May 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

    First recorded

Apr 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Shanghai Henlius Biotech
Data source: Shanghai Henlius Biotech

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations