Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria (PKU)
A Phase 1/2a, First-in-human, Oral Single and Multiple Dose-escalation, Randomized, Double-blinded, Placebo-controlled Study of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria to Evaluate Safety, Tolerability, Kinetics, and Pharmacodynamics
Sponsor: Synlogic
A PHASE1/PHASE2 clinical study on Healthy and Phenylketonuria, this trial is completed. The trial is conducted by Synlogic and has accumulated 12 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.
Status Flow
Change History
12 versions recorded-
Sep 2024 — Present [monthly]
Completed PHASE1/PHASE2
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE1/PHASE2
Phase: PHASE1_PHASE2 → PHASE1/PHASE2
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Apr 2022 — Jul 2024 [monthly]
Completed PHASE1_PHASE2
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Jun 2021 — Apr 2022 [monthly]
Completed PHASE1_PHASE2
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Jan 2021 — Jun 2021 [monthly]
Completed PHASE1_PHASE2
▶ Show 7 earlier versions
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Aug 2020 — Jan 2021 [monthly]
Completed PHASE1_PHASE2
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Aug 2019 — Aug 2020 [monthly]
Completed PHASE1_PHASE2
Status: Recruiting → Completed
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Jun 2019 — Aug 2019 [monthly]
Recruiting PHASE1_PHASE2
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Feb 2019 — Jun 2019 [monthly]
Recruiting PHASE1_PHASE2
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Dec 2018 — Feb 2019 [monthly]
Recruiting PHASE1_PHASE2
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Jul 2018 — Dec 2018 [monthly]
Recruiting PHASE1_PHASE2
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Jun 2018 — Jul 2018 [monthly]
Recruiting PHASE1_PHASE2
First recorded
Apr 2018
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Synlogic
For direct contact, visit the study record on ClinicalTrials.gov .