deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT03518073

A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease

Assessment of Safety, Tolerability, and Efficacy of LY3303560 in Early Symptomatic Alzheimer's Disease

Sponsor: Eli Lilly and Company

Conditions Alzheimer Disease (AD)
Interventions Placebo Zagotenemab
Updated 35 times since 2018 Last updated: Aug 12, 2022 Started: Apr 30, 2018 Primary completion: Aug 23, 2021 Completion: Oct 25, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Alzheimer Disease (AD) and is currently completed. Eli Lilly and Company leads this study, which shows 35 recorded versions since 2018 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Jan 2019 · 31 days · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~May 2019 · 2 months · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Nov 2021 · 10 months · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Sep 2022 · 9 months · monthly snapshot~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

35 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE2

  5. Dec 2021 — Sep 2022 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

▶ Show 30 earlier versions

  1. Nov 2021 — Dec 2021 [monthly]

    Active Not Recruiting PHASE2

  2. Jan 2021 — Nov 2021 [monthly]

    Active Not Recruiting PHASE2

  3. Nov 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

  4. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE2

  5. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE2

  6. Aug 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE2

  7. Jul 2020 — Aug 2020 [monthly]

    Active Not Recruiting PHASE2

  8. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

  9. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE2

  10. Apr 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE2

  11. Mar 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE2

  12. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  13. Jan 2020 — Feb 2020 [monthly]

    Active Not Recruiting PHASE2

  14. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2

  15. Nov 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE2

  16. Oct 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  17. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE2

  18. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  19. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  20. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  21. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  22. Mar 2019 — May 2019 [monthly]

    Recruiting PHASE2

  23. Feb 2019 — Mar 2019 [monthly]

    Recruiting PHASE2

  24. Jan 2019 — Feb 2019 [monthly]

    Recruiting PHASE2

  25. Dec 2018 — Jan 2019 [monthly]

    Recruiting PHASE2

  26. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

  27. Oct 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

  28. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE2

  29. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

  30. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE2

    First recorded

Apr 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eli Lilly and Company
Data source: Eli Lilly and Company

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Allentown, United States , Atlantis, United States , Aventura, United States , Baltimore, United States , Bennington, United States , Boston, United States , Chesterfield, United States , Chicago, United States , Cincinnati, United States , Columbus, United States and 48 more locations