deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT03521570

Intensity-Modulated Radiation Therapy & Nivolumab for Recurrent or Second Primary Head & Neck Squamous Cell Cancer

Phase II Study of IMRT Re-Irradiation With Concurrent/Adjuvant Nivolumab in Patients With Locoregionally Recurrent or Second Primary Squamous Cell Cancer of the Head and Neck

Sponsor: Bristol-Myers Squibb

Interventions IMRT Nivolumab
Updated 13 times since 2018 Last updated: Sep 14, 2024 Started: Jun 28, 2018 Primary completion: Jul 25, 2022 Completion: Sep 7, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03521570, this PHASE2 trial focuses on Recurrent Head and Neck Squamous Cell Carcinoma and remains completed. Sponsored by Bristol-Myers Squibb, it has been updated 13 times since 2018, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshot~Aug 2018 – ~Jun 2019 · 10 months · monthly snapshot~Jun 2019 – ~Sep 2019 · 3 months · monthly snapshot~Sep 2019 – ~Jan 2020 · 4 months · monthly snapshot~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Mar 2022 · 11 months · monthly snapshot~Mar 2022 – ~Feb 2023 · 11 months · monthly snapshot~Feb 2023 – ~Jun 2023 · 4 months · monthly snapshot~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – present · 21 months · monthly snapshot

Change History

13 versions recorded
  1. Oct 2024 — Present [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Jun 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

Show 8 earlier versions
  1. Mar 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Apr 2021 — Mar 2022 [monthly]

    Recruiting PHASE2

  3. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  4. Jan 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  5. Sep 2019 — Jan 2020 [monthly]

    Recruiting PHASE2

  6. Jun 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  7. Aug 2018 — Jun 2019 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  8. Jun 2018 — Aug 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bristol-Myers Squibb
  • Emory University
  • Medical College of Wisconsin
  • National Cancer Institute (NCI)
  • National Institutes of Health (NIH)
  • The Cleveland Clinic
Data source: Emory University

For direct contact, visit the study record on ClinicalTrials.gov .