deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 1-arm NCT03523312

Use of High-dose Radiation Therapy Plus Chemotherapy to Improve the Likelihood of Surgical Treatment in Patients With Locally Advanced Pancreatic Cancer (MAIBE)

Maximal Ablative Irradiation Because of Encasement (MAIBE) for Patients With Potentially Resectable Locally Advanced Pancreatic Cancer

Sponsor: Memorial Sloan Kettering Cancer Center

Conditions Pancreatic Cancer
Interventions Hypofractionated ablative IMRT (HFA-IMRT) capecitabine
Updated 15 times since 2018 Last updated: May 1, 2025 Started: Apr 30, 2018 Primary completion: Apr 30, 2026 Completion: Apr 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Pancreatic Cancer, this trial is ongoing. The trial is conducted by Memorial Sloan Kettering Cancer Center and has accumulated 15 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshot~Nov 2018 – ~Feb 2019 · 3 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~May 2020 · 12 months · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Nov 2021 · 6 months · monthly snapshot~Nov 2021 – ~Jun 2022 · 7 months · monthly snapshot~Jun 2022 – ~Jun 2023 · 12 months · monthly snapshot~Jun 2023 – ~Aug 2023 · 2 months · monthly snapshot~Aug 2023 – ~Jun 2024 · 10 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – present · 12 months · monthly snapshot

Change History

15 versions recorded

  1. Jun 2025 — Present [monthly]

    Active Not Recruiting PHASE2

  2. Sep 2024 — Jun 2025 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Aug 2023 — Jun 2024 [monthly]

    Active Not Recruiting PHASE2

▶ Show 10 earlier versions

  1. Jun 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Jun 2022 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Nov 2021 — Jun 2022 [monthly]

    Recruiting PHASE2

  4. May 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  5. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE2

  6. May 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  7. May 2019 — May 2020 [monthly]

    Recruiting PHASE2

  8. Feb 2019 — May 2019 [monthly]

    Recruiting PHASE2

  9. Nov 2018 — Feb 2019 [monthly]

    Recruiting PHASE2

  10. Jun 2018 — Nov 2018 [monthly]

    Recruiting PHASE2

    First recorded

Apr 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Memorial Sloan Kettering Cancer Center
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations