deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 1-arm NCT03531736

T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia

Allogeneic Hematopoietic Stem Cell Transplantation of α/β T-Lymphocyte Depleted Graft Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia

Sponsor: Memorial Sloan Kettering Cancer Center

Conditions Myeloid Diseases
Interventions Allogeneic Hematopoietic Stem Cell Transplantation Antithymocyte globulin (Rabbit) Rituxan cyclophosphamide fludarabine total body irradiation
Updated 17 times since 2018 Last updated: Aug 18, 2025 Started: May 9, 2018 Primary completion: May 31, 2026 Completion: May 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Myeloid Diseases, this trial is ongoing. The trial is conducted by Memorial Sloan Kettering Cancer Center and has accumulated 17 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Apr 2019 · 4 months · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Feb 2020 · 7 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Feb 2023 · 12 months · monthly snapshot~Feb 2023 – ~Jun 2023 · 4 months · monthly snapshot~Jun 2023 – ~Dec 2023 · 6 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Sep 2025 · 8 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

17 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Jan 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Sep 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Dec 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

▶ Show 12 earlier versions

  1. Jun 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  2. Feb 2023 — Jun 2023 [monthly]

    Recruiting PHASE1

  3. Feb 2022 — Feb 2023 [monthly]

    Recruiting PHASE1

  4. Sep 2021 — Feb 2022 [monthly]

    Recruiting PHASE1

  5. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

  6. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  7. Mar 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

  8. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE1

  9. Jul 2019 — Feb 2020 [monthly]

    Recruiting PHASE1

  10. Apr 2019 — Jul 2019 [monthly]

    Recruiting PHASE1

  11. Dec 2018 — Apr 2019 [monthly]

    Recruiting PHASE1

  12. Jun 2018 — Dec 2018 [monthly]

    Recruiting PHASE1

    First recorded

May 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Memorial Sloan Kettering Cancer Center
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations