deltatrials
Unknown PHASE2 NCT03544723

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

A Phase 2, Multi-Center, Open Label Study to Evaluate Adenoviral p53 (Ad-p53) in Combination With Immune Checkpoint Inhibitor Therapy in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Tumors Approved for Anti-PD-1 or Anti-PD-L1 Therapy

Sponsor: MultiVir, Inc.

Interventions Ad-p53
Updated 10 times since 2018 Last updated: Jun 5, 2020 Started: Oct 1, 2018 Primary completion: Jun 30, 2022 Completion: Dec 31, 2022

A PHASE2 clinical study on Lymphoma and Solid Tumor, this trial is ongoing. The trial is conducted by MultiVir, Inc. and has accumulated 10 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshotRecruiting~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshotRecruiting~Oct 2018 – ~Apr 2019 · 6 months · monthly snapshotRecruiting~Apr 2019 – ~Mar 2020 · 11 months · monthly snapshotRecruiting~Mar 2020 – ~Jul 2020 · 4 months · monthly snapshotRecruiting~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2023 · 25 months · monthly snapshotRecruiting~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – present · 19 months · monthly snapshotUnknown

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Unknown PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2

    Status: Unknown StatusUnknown

  3. Feb 2023 — Jul 2024 [monthly]

    Unknown Status PHASE2

    Status: RecruitingUnknown Status

  4. Jan 2021 — Feb 2023 [monthly]

    Recruiting PHASE2

  5. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

Show 5 earlier versions
  1. Mar 2020 — Jul 2020 [monthly]

    Recruiting PHASE2

  2. Apr 2019 — Mar 2020 [monthly]

    Recruiting PHASE2

  3. Oct 2018 — Apr 2019 [monthly]

    Recruiting PHASE2

  4. Sep 2018 — Oct 2018 [monthly]

    Recruiting PHASE2

  5. Jul 2018 — Sep 2018 [monthly]

    Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • MultiVir, Inc.
Data source: MultiVir, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .