deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT03558984

D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery

Prospective, Multicenter, Randomized, Parallel Controlled, Two Arms, Single Blind, Study to Assess the Efficacy and Safety of D-PLEX Administered Concomitantly With the SOC IV Prophylactic Antibiotic Treatment vs. SOC in Prevention of Post-Cardiac Surgery Sternal Infections

Sponsor: PolyPid Ltd.

Updated 10 times since 2018 Last updated: Nov 9, 2022 Started: Dec 17, 2019 Primary completion: Oct 24, 2022 Completion: Oct 24, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

company prioritization reasons

This PHASE3 trial investigates Cardiac Surgery and Sternal Infection and is currently terminated or withdrawn. PolyPid Ltd. leads this study, which shows 10 recorded versions since 2019 — indicating substantial longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Jul 2018 – ~Apr 2019 · 9 months · monthly snapshotNot Yet Recruiting~Apr 2019 – ~Oct 2019 · 6 months · monthly snapshotNot Yet Recruiting~Oct 2019 – ~Jun 2020 · 8 months · monthly snapshotNot Yet Recruiting~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotRecruiting~Jan 2021 – ~Nov 2021 · 10 months · monthly snapshotRecruiting~Nov 2021 – ~Dec 2022 · 13 months · monthly snapshotRecruiting~Dec 2022 – ~Jul 2024 · 19 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 12 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Dec 2022 — Jul 2024 [monthly]

    Terminated PHASE3

    Status: RecruitingTerminated

  5. Nov 2021 — Dec 2022 [monthly]

    Recruiting PHASE3

Show 5 earlier versions
  1. Jan 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  2. Jun 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  3. Oct 2019 — Jun 2020 [monthly]

    Not Yet Recruiting PHASE3

  4. Apr 2019 — Oct 2019 [monthly]

    Not Yet Recruiting PHASE3

  5. Jul 2018 — Apr 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • PolyPid Ltd.
Data source: PolyPid Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .