deltatrials
Terminated PHASE4 INTERVENTIONAL 5-arm NCT03560232

Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens

A Randomized Controlled Trial Assessing Noninferiority of Three Antimicrobial Regimens for the Treatment of Grade III Open Fractures

Sponsor: Mercy Health Ohio

Conditions Open Fracture Post-Op Wound Infection
Interventions Ampicillin/sulbactam Cefazolin + Gentamicin Ceftriaxone Clindamycin + Gentamicin Piperacillin/tazobactam
Updated 7 times since 2018 Last updated: Sep 9, 2020 Started: Jul 9, 2018 Primary completion: Feb 19, 2020 Completion: Feb 19, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Unable to recruit patients in a timely fashion and unable to recruit sufficient patients

Other terminated trials from Mercy Health Ohio

See all terminations from Mercy Health Ohio

This PHASE4 trial investigates Open Fracture and Post-Op Wound Infection and is currently terminated or withdrawn. Mercy Health Ohio leads this study, which shows 7 recorded versions since 2018 — indicating limited longitudinal coverage. Longitudinal tracking of infectious disease trials helps identify durability of treatment effects.

Status Flow

~Jul 2018 – ~Sep 2018 · 2 months · monthly snapshotNot Yet Recruiting~Sep 2018 – ~Oct 2019 · 13 months · monthly snapshotRecruiting~Oct 2019 – ~Oct 2020 · 12 months · monthly snapshotRecruiting~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

7 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated PHASE4

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE4

  3. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE4

  4. Oct 2020 — Jan 2021 [monthly]

    Terminated PHASE4

    Status: Recruiting → Terminated

  5. Oct 2019 — Oct 2020 [monthly]

    Recruiting PHASE4

▶ Show 2 earlier versions

  1. Sep 2018 — Oct 2019 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  2. Jul 2018 — Sep 2018 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mercy Health Ohio
Data source: Mercy Health Ohio

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations