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Terminated NA INTERVENTIONAL 2-arm NCT03584295

Early Extubation by ECCO2R Compared to IMV in Patients with Severe Acute Exacerbation of COPD (X-COPD)

A Multicentre, Randomized-controlled Trial of EXtracorporeal CO2 Removal to Facilitate Early Extubation Compared to Invasive Mechanical Ventilation in Patients with Severe Acute Exacerbation of COPD (X-COPD)

Sponsor: Winicker Norimed GmbH

Updated 11 times since 2018 Last updated: Mar 13, 2025 Started: Feb 7, 2023 Primary completion: Nov 1, 2024 Completion: Nov 25, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Business decision

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This NA trial investigates COPD Exacerbation and is currently terminated or withdrawn. Winicker Norimed GmbH leads this study, which shows 11 recorded versions since 2023 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Aug 2018 – ~Jan 2021 · 29 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotNot Yet Recruiting~Sep 2021 – ~Jan 2022 · 4 months · monthly snapshotNot Yet Recruiting~Jan 2022 – ~Sep 2022 · 8 months · monthly snapshotNot Yet Recruiting~Sep 2022 – ~Mar 2023 · 6 months · monthly snapshotNot Yet Recruiting~Mar 2023 – ~Mar 2024 · 12 months · monthly snapshotRecruiting~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshotRecruiting~Apr 2025 – ~Sep 2025 · 5 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated NA

  2. Apr 2025 — Sep 2025 [monthly]

    Terminated NA

    Status: RecruitingTerminated

  3. Sep 2024 — Apr 2025 [monthly]

    Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  5. Mar 2024 — Jul 2024 [monthly]

    Recruiting NA

Show 6 earlier versions
  1. Mar 2023 — Mar 2024 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  2. Sep 2022 — Mar 2023 [monthly]

    Not Yet Recruiting NA

  3. Jan 2022 — Sep 2022 [monthly]

    Not Yet Recruiting NA

  4. Sep 2021 — Jan 2022 [monthly]

    Not Yet Recruiting NA

  5. Jan 2021 — Sep 2021 [monthly]

    Not Yet Recruiting NA

  6. Aug 2018 — Jan 2021 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Winicker Norimed GmbH
  • Xenios AG
Data source: Fresenius Medical Care Deutschland GmbH

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations