deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT03608878

Adagloxad Simolenin/OBI-821 in Combination With TACE Therapy in HCC Patients With GALNT14-rs9679162-non-TT Genotype

Randomized, Controlled, Open Label, Clinical Trial for Adagloxad Simolenin/OBI-821 in Combination With TACE Therapy in Hepatocellular Carcinoma Patients With GALNT14-rs9679162-non-TT Genotype

Sponsor: Chang Gung Memorial Hospital

Updated 9 times since 2018 Last updated: May 4, 2021 Started: Apr 26, 2019 Primary completion: Dec 31, 2019 Completion: Dec 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The biopsies in the first 5 screened patients were all negative for Globo-H, of which positive is required to include the patients.

A PHASE2 clinical study on Hepatocellular Carcinoma, this trial is terminated or withdrawn. The trial is conducted by Chang Gung Memorial Hospital and has accumulated 9 data snapshots since 2019. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Aug 2018 – ~Feb 2019 · 6 months · monthly snapshotNot Yet Recruiting~Feb 2019 – ~Jan 2020 · 11 months · monthly snapshotNot Yet Recruiting~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshotRecruiting~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshotRecruiting~Jun 2021 – ~Dec 2021 · 6 months · monthly snapshotTerminated~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jun 2021 — Dec 2021 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

Show 4 earlier versions
  1. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  2. Jan 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Feb 2019 — Jan 2020 [monthly]

    Not Yet Recruiting PHASE2

  4. Aug 2018 — Feb 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Chang Gung Memorial Hospital
Data source: Chang Gung Memorial Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations