deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT03628066

Biological and Clinical Effects of Palbociclib With Ovarian Suppression and Letrozole in the Neoadjuvant Treatment of Breast Cancer

An Assessment of the Biological and Clinical Effects of Palbociclib (PD 0332991) With Ovarian Suppression and Letrozole in the Neoadjuvant Treatment of Patients With Premenopausal Estrogen-Receptor Positive/HER2-Negative Primary Breast Cancer

Sponsor: Genomic Health®, Inc.

Conditions Breast Cancer
Updated 14 times since 2018 Last updated: Apr 13, 2022 Started: Oct 22, 2018 Primary completion: Nov 30, 2020 Completion: Jan 30, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Breast Cancer, this trial is completed. The trial is conducted by Genomic Health®, Inc. and has accumulated 14 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Sep 2018 – ~Feb 2019 · 5 months · monthly snapshot~Feb 2019 – ~Apr 2019 · 59 days · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Dec 2019 · 3 months · monthly snapshot~Dec 2019 – ~Oct 2020 · 10 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~May 2022 · 12 months · monthly snapshot~May 2022 – ~Jul 2024 · 26 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

14 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. May 2022 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. May 2021 — May 2022 [monthly]

    Active Not Recruiting PHASE2

Show 9 earlier versions
  1. Jan 2021 — May 2021 [monthly]

    Active Not Recruiting PHASE2

  2. Oct 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Dec 2019 — Oct 2020 [monthly]

    Recruiting PHASE2

  4. Sep 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  5. Jul 2019 — Sep 2019 [monthly]

    Recruiting PHASE2

  6. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE2

  7. Apr 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  8. Feb 2019 — Apr 2019 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  9. Sep 2018 — Feb 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Genomic Health®, Inc.
  • NSABP Foundation Inc
  • Pfizer
Data source: NSABP Foundation Inc

For direct contact, visit the study record on ClinicalTrials.gov .