deltatrials
Recruiting PHASE2 INTERVENTIONAL 1-arm NCT03630211

Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis (SSc)

Autologous Stem Cell Transplantation With CD34-Selected Peripheral Blood Stem Cells (PBSC) in Patients With Treatment Resistant Systemic Sclerosis (SSc)

Sponsor: Paul Szabolcs

Conditions Diffuse Sclerosis Systemic Interstitial Lung Disease Pulmonary Hypertension Systemic Sclerosis
Interventions Alemtuzumab Anti Thymocyte Globulin Cyclophosphamide GM-CSF Intravenous immunoglobulin Mesna Rituximab Thiotepa Total Body Irradiation
Updated 16 times since 2018 Last updated: Oct 13, 2025 Started: Jul 31, 2018 Primary completion: Aug 1, 2026 Completion: Aug 1, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Diffuse Sclerosis Systemic and Interstitial Lung Disease, this trial is actively recruiting participants. The trial is conducted by Paul Szabolcs and has accumulated 16 data snapshots since 2018. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

~Sep 2018 – ~Apr 2019 · 7 months · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Apr 2020 · 11 months · monthly snapshot~Apr 2020 – ~Dec 2020 · 8 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Nov 2021 · 10 months · monthly snapshot~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshot~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshot~Sep 2022 – ~Sep 2023 · 12 months · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Nov 2025 · 5 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshot

Change History

16 versions recorded

  1. Nov 2025 — Present [monthly]

    Recruiting PHASE2

  2. Jun 2025 — Nov 2025 [monthly]

    Recruiting PHASE2

  3. Apr 2025 — Jun 2025 [monthly]

    Recruiting PHASE2

  4. Sep 2024 — Apr 2025 [monthly]

    Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

▶ Show 11 earlier versions

  1. Oct 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

  2. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE2

  3. Sep 2022 — Sep 2023 [monthly]

    Recruiting PHASE2

  4. Feb 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  5. Nov 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

  6. Jan 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  7. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  8. Apr 2020 — Dec 2020 [monthly]

    Recruiting PHASE2

  9. May 2019 — Apr 2020 [monthly]

    Recruiting PHASE2

  10. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE2

  11. Sep 2018 — Apr 2019 [monthly]

    Recruiting PHASE2

    First recorded

Jul 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Paul Szabolcs
Data source: University of Pittsburgh

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations