deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT03633396

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Palmoplantar Pustulosis (POPLAR)

A Phase 2, Randomized, Placebo-controlled, Double-blind, Multiple Dose Study to Evaluate the Efficacy and Safety of ANB019 in Subjects With Palmoplantar Pustulosis

Sponsor: Vanda Pharmaceuticals

Updated 14 times since 2018 Last updated: Sep 2, 2025 Started: May 20, 2019 Primary completion: Apr 23, 2021 Completion: Apr 23, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Palmoplantar Pustulosis and is currently completed. Vanda Pharmaceuticals leads this study, which shows 14 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2018 – ~Feb 2019 · 5 months · monthly snapshot~Feb 2019 – ~May 2019 · 3 months · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Sep 2020 · 13 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jun 2022 · 16 months · monthly snapshot~Jun 2022 – ~Jul 2024 · 25 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – present · 10 months · monthly snapshot

Change History

14 versions recorded
  1. Oct 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2025 — Oct 2025 [monthly]

    Completed PHASE2

  3. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  5. Jun 2022 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

Show 9 earlier versions
  1. Feb 2021 — Jun 2022 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2

  3. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  4. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

  5. Aug 2019 — Sep 2020 [monthly]

    Recruiting PHASE2

  6. Jun 2019 — Aug 2019 [monthly]

    Recruiting PHASE2

  7. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE2

  8. Feb 2019 — May 2019 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  9. Sep 2018 — Feb 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Vanda Pharmaceuticals
Data source: Vanda Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .