Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy
A Phase 2, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of KD025 in Subjects With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy (The ROCKstar Study)
Sponsor: Kadmon, a Sanofi Company
Terminated
The sponsor has decided to prematurely terminate the study due to the challenges encountered in recruiting adolescent participants. This decision was made without any safety concerns.
Other terminated trials from Kadmon, a Sanofi Company
Listed as NCT03640481, this PHASE2 trial focuses on Chronic Graft-versus-host-disease and remains terminated or withdrawn. Sponsored by Kadmon, a Sanofi Company, it has been updated 31 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Status Flow
Change History
31 versions recorded-
Sep 2025 — Present [monthly]
Terminated PHASE2
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Jan 2025 — Sep 2025 [monthly]
Terminated PHASE2
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Sep 2024 — Jan 2025 [monthly]
Terminated PHASE2
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Jul 2024 — Sep 2024 [monthly]
Terminated PHASE2
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Jan 2024 — Jul 2024 [monthly]
Terminated PHASE2
Status: Active Not Recruiting → Terminated
▶ Show 26 earlier versions
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Dec 2023 — Jan 2024 [monthly]
Active Not Recruiting PHASE2
Status: Recruiting → Active Not Recruiting
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Sep 2023 — Dec 2023 [monthly]
Recruiting PHASE2
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Jul 2023 — Sep 2023 [monthly]
Recruiting PHASE2
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Apr 2023 — Jul 2023 [monthly]
Recruiting PHASE2
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Sep 2022 — Apr 2023 [monthly]
Recruiting PHASE2
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Jul 2022 — Sep 2022 [monthly]
Recruiting PHASE2
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Jun 2022 — Jul 2022 [monthly]
Recruiting PHASE2
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May 2022 — Jun 2022 [monthly]
Recruiting PHASE2
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Apr 2022 — May 2022 [monthly]
Recruiting PHASE2
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Sep 2021 — Apr 2022 [monthly]
Recruiting PHASE2
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Apr 2021 — Sep 2021 [monthly]
Recruiting PHASE2
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Jan 2021 — Apr 2021 [monthly]
Recruiting PHASE2
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Nov 2020 — Jan 2021 [monthly]
Recruiting PHASE2
Status: Active Not Recruiting → Recruiting
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Aug 2020 — Nov 2020 [monthly]
Active Not Recruiting PHASE2
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Apr 2020 — Aug 2020 [monthly]
Active Not Recruiting PHASE2
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Feb 2020 — Apr 2020 [monthly]
Active Not Recruiting PHASE2
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Oct 2019 — Feb 2020 [monthly]
Active Not Recruiting PHASE2
Status: Recruiting → Active Not Recruiting
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Sep 2019 — Oct 2019 [monthly]
Recruiting PHASE2
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Aug 2019 — Sep 2019 [monthly]
Recruiting PHASE2
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Jul 2019 — Aug 2019 [monthly]
Recruiting PHASE2
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Jun 2019 — Jul 2019 [monthly]
Recruiting PHASE2
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May 2019 — Jun 2019 [monthly]
Recruiting PHASE2
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Apr 2019 — May 2019 [monthly]
Recruiting PHASE2
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Mar 2019 — Apr 2019 [monthly]
Recruiting PHASE2
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Jan 2019 — Mar 2019 [monthly]
Recruiting PHASE2
Status: Not Yet Recruiting → Recruiting
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Sep 2018 — Jan 2019 [monthly]
Not Yet Recruiting PHASE2
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Kadmon, a Sanofi Company
For direct contact, visit the study record on ClinicalTrials.gov .