COBRA-Slim With or Without Fast Access to TNF Blockade for Remission Induction in Early RA (CareRA2020)
Effectiveness of a Combination of Methotrexate and a Step Down Glucocorticoid Regimen (COBRA-Slim) for Remission Induction in Patients With Early Rheumatoid Arthritis (RA), With or Without Fast Access to 24 Weeks of Tumor Necrosis Factor (TNF) Blockade in Insufficient Responders, a Randomized, Multicenter, Pragmatic Trial
Sponsor: Belgium Health Care Knowledge Centre
Listed as NCT03649061, this PHASE4 trial focuses on Arthritis, Rheumatoid and remains completed. Sponsored by Belgium Health Care Knowledge Centre, it has been updated 10 times since 2018, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Status Flow
Change History
10 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE4
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Jul 2025 — Sep 2025 [monthly]
Completed PHASE4
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Sep 2024 — Jul 2025 [monthly]
Completed PHASE4
-
Jul 2024 — Sep 2024 [monthly]
Completed PHASE4
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Oct 2022 — Jul 2024 [monthly]
Completed PHASE4
▶ Show 5 earlier versions
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Sep 2022 — Oct 2022 [monthly]
Completed PHASE4
Status: Active Not Recruiting → Completed
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Jun 2022 — Sep 2022 [monthly]
Active Not Recruiting PHASE4
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Jan 2021 — Jun 2022 [monthly]
Active Not Recruiting PHASE4
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Dec 2020 — Jan 2021 [monthly]
Active Not Recruiting PHASE4
Status: Recruiting → Active Not Recruiting
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Sep 2018 — Dec 2020 [monthly]
Recruiting PHASE4
First recorded
Jun 2018
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Belgium Health Care Knowledge Centre
- P. Verschueren
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Aalst, Belgium , Bonheiden, Belgium , Bruges, Belgium , Brussels, Belgium , Genk, Belgium , Gilly, Belgium , Hasselt, Belgium , Herentals, Belgium , Leuven, Belgium , Liège, Belgium and 3 more locations