deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT03668236

The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial (CLASSIC)

Sponsor: Anders Perner, MD, PhD

Conditions Septic Shock
Interventions Isotonic crystalloids
Updated 18 times since 2018 Last updated: Feb 21, 2025 Started: Nov 27, 2018 Primary completion: Feb 14, 2022 Completion: Nov 16, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on Septic Shock, this trial is completed. The trial is conducted by Anders Perner, MD, PhD and has accumulated 18 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Oct 2018 – ~Dec 2018 · 2 months · monthly snapshot~Dec 2018 – ~Apr 2019 · 4 months · monthly snapshot~Apr 2019 – ~Jul 2019 · 3 months · monthly snapshot~Jul 2019 – ~Sep 2019 · 2 months · monthly snapshot~Sep 2019 – ~Jan 2020 · 4 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~Nov 2020 · 8 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Oct 2021 · 8 months · monthly snapshot~Oct 2021 – ~Mar 2022 · 5 months · monthly snapshot~Mar 2022 – ~May 2022 · 2 months · monthly snapshot~May 2022 – ~May 2024 · 24 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Sep 2025 · 6 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

18 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Mar 2025 — Sep 2025 [monthly]

    Completed PHASE4

    Status: Unknown → Completed

  3. Sep 2024 — Mar 2025 [monthly]

    Unknown PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE4

    Status: Unknown Status → Unknown

  5. May 2024 — Jul 2024 [monthly]

    Unknown Status PHASE4

    Status: Active Not Recruiting → Unknown Status

▶ Show 13 earlier versions

  1. May 2022 — May 2024 [monthly]

    Active Not Recruiting PHASE4

  2. Mar 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE4

    Status: Recruiting → Active Not Recruiting

  3. Oct 2021 — Mar 2022 [monthly]

    Recruiting PHASE4

  4. Feb 2021 — Oct 2021 [monthly]

    Recruiting PHASE4

  5. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE4

  6. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE4

  7. Mar 2020 — Nov 2020 [monthly]

    Recruiting PHASE4

  8. Jan 2020 — Mar 2020 [monthly]

    Recruiting PHASE4

  9. Sep 2019 — Jan 2020 [monthly]

    Recruiting PHASE4

  10. Jul 2019 — Sep 2019 [monthly]

    Recruiting PHASE4

  11. Apr 2019 — Jul 2019 [monthly]

    Recruiting PHASE4

  12. Dec 2018 — Apr 2019 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  13. Oct 2018 — Dec 2018 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Anders Perner, MD, PhD
  • Centre for Research in Intensive Care (CRIC)
  • Rigshospitalet, Denmark
  • Scandinavian Critical Care Trials Group
Data source: Scandinavian Critical Care Trials Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aalborg, Denmark , Ancona, Italy , Basel, Switzerland , Bergamo, Italy , Bern, Switzerland , Brussels, Belgium , Castellanza, Italy , Copenhagen, Denmark , Gothenburg, Sweden , Grålum, Norway and 18 more locations