deltatrials
Recruiting PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT03676504

Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR

Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Lymphocytes Transduced by RV-SFG.CD19.CD28.4-1BBzeta Retroviral Vector - a Unicenter Phase I/II Clinical Trial

Sponsor: University Hospital Heidelberg

Updated 8 times since 2018 Last updated: Jul 26, 2024 Started: Sep 7, 2018 Primary completion: Dec 31, 2026 Completion: Dec 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1/PHASE2 clinical study on Acute Lymphoblastic Leukemia, Adult and Acute Lymphoblastic Leukemia, Pediatric, this trial is actively recruiting participants. The trial is conducted by University Hospital Heidelberg and has accumulated 8 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Oct 2018 – ~Nov 2019 · 13 months · monthly snapshotRecruiting~Nov 2019 – ~Dec 2020 · 13 months · monthly snapshotRecruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Jul 2023 · 30 months · monthly snapshotRecruiting~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshotRecruiting~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotRecruiting~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotRecruiting~Sep 2024 – present · 22 months · monthly snapshotRecruiting

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Recruiting PHASE1/PHASE2

  2. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

  3. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Jul 2023 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jan 2021 — Jul 2023 [monthly]

    Recruiting PHASE1_PHASE2

Show 3 earlier versions
  1. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  2. Nov 2019 — Dec 2020 [monthly]

    Recruiting PHASE1_PHASE2

  3. Oct 2018 — Nov 2019 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Sep 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University Hospital Heidelberg
Data source: University Hospital Heidelberg

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations