deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT03680521

Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma

A Phase 2 Study of Sitravatinib in Combination With Nivolumab in Patients Undergoing Nephrectomy for Locally-Advanced Clear Cell Renal Cell Carcinoma

Sponsor: Mirati Therapeutics Inc.

Conditions Clear Cell Renal Cell Carcinoma
Interventions Nivolumab Sitravatinib
Updated 11 times since 2018 Last updated: Sep 11, 2023 Started: Oct 10, 2018 Primary completion: Apr 27, 2020 Completion: May 18, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Clear Cell Renal Cell Carcinoma, this trial is completed. The trial is conducted by Mirati Therapeutics Inc. and has accumulated 11 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshotNot Yet Recruiting~Nov 2018 – ~Nov 2019 · 12 months · monthly snapshotRecruiting~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshotRecruiting~Dec 2019 – ~Jul 2020 · 7 months · monthly snapshotRecruiting~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshotActive Not Recruiting~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshotActive Not Recruiting~Jun 2021 – ~Jun 2023 · 24 months · monthly snapshotActive Not Recruiting~Jun 2023 – ~Nov 2023 · 5 months · monthly snapshotUnknown Status~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

11 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Nov 2023 — Jul 2024 [monthly]

    Completed PHASE2

    Status: Unknown Status → Completed

  4. Jun 2023 — Nov 2023 [monthly]

    Unknown Status PHASE2

    Status: Active Not Recruiting → Unknown Status

  5. Jun 2021 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

▶ Show 6 earlier versions

  1. Jan 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE2

  2. Jul 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Dec 2019 — Jul 2020 [monthly]

    Recruiting PHASE2

  4. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE2

  5. Nov 2018 — Nov 2019 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  6. Oct 2018 — Nov 2018 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mirati Therapeutics Inc.
Data source: Mirati Therapeutics Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations