deltatrials
Unknown PHASE2 INTERVENTIONAL 1-arm NCT03691714

Durvalumab (MEDI4736) With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

An Open-label, Phase II Study of Durvalumab (MEDI4736) in Combination With Cetuximab in Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Sponsor: AstraZeneca

Updated 12 times since 2018 Last updated: Dec 6, 2023 Started: Oct 23, 2018 Primary completion: Dec 31, 2024 Completion: Dec 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Head and Neck Cancer and Head and Neck Neoplasms, this trial is ongoing. The trial is conducted by AstraZeneca and has accumulated 12 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshotRecruiting~Dec 2018 – ~Dec 2019 · 12 months · monthly snapshotRecruiting~Dec 2019 – ~Jan 2021 · 13 months · monthly snapshotRecruiting~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshotRecruiting~Apr 2021 – ~Dec 2021 · 8 months · monthly snapshotRecruiting~Dec 2021 – ~Nov 2022 · 11 months · monthly snapshotActive Not Recruiting~Nov 2022 – ~Jun 2023 · 7 months · monthly snapshotActive Not Recruiting~Jun 2023 – ~Jan 2024 · 7 months · monthly snapshotActive Not Recruiting~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Jan 2026 · 16 months · monthly snapshotActive Not Recruiting~Jan 2026 – present · 7 months · monthly snapshotUnknown

Change History

12 versions recorded
  1. Jan 2026 — Present [monthly]

    Unknown PHASE2

    Status: Active Not RecruitingUnknown

  2. Sep 2024 — Jan 2026 [monthly]

    Active Not Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

  4. Jan 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jun 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE2

Show 7 earlier versions
  1. Nov 2022 — Jun 2023 [monthly]

    Active Not Recruiting PHASE2

  2. Dec 2021 — Nov 2022 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  3. Apr 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

  4. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

  5. Dec 2019 — Jan 2021 [monthly]

    Recruiting PHASE2

  6. Dec 2018 — Dec 2019 [monthly]

    Recruiting PHASE2

  7. Nov 2018 — Dec 2018 [monthly]

    Recruiting PHASE2

    First recorded

Oct 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
  • Trisha Wise-Draper
Data source: University of Cincinnati

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations