deltatrials
Unknown PHASE3 INTERVENTIONAL 2-arm NCT03700788

2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament

Use of 2% Chlorhexidine (CHX) as Intracanal Medicament in Endodontic Emergencies and to Compare Its Use and Effectiveness With CaOH2 (CH) Calcium Hydroxide Paste

Sponsor: University of Southern California

Conditions Apical Periodontitis
Interventions Calcium Hydroxide Chlorhexidine
Updated 8 times since 2018 Last updated: Mar 6, 2023 Started: May 30, 2023 Primary completion: Jun 30, 2025 Completion: Aug 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Apical Periodontitis and is currently ongoing. University of Southern California leads this study, which shows 8 recorded versions since 2023 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Nov 2018 – ~May 2019 · 6 months · monthly snapshotEnrolling By Invitation~May 2019 – ~Jan 2021 · 20 months · monthly snapshotEnrolling By Invitation~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotEnrolling By Invitation~Mar 2022 – ~Apr 2023 · 13 months · monthly snapshotUnknown Status~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotNot Yet Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotNot Yet Recruiting~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshotNot Yet Recruiting~Oct 2025 – present · 9 months · monthly snapshotUnknown

Change History

8 versions recorded

  1. Oct 2025 — Present [monthly]

    Unknown PHASE3

    Status: Not Yet Recruiting → Unknown

  2. Sep 2024 — Oct 2025 [monthly]

    Not Yet Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE3

  4. Apr 2023 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE3

    Status: Unknown Status → Not Yet Recruiting

  5. Mar 2022 — Apr 2023 [monthly]

    Unknown Status PHASE3

    Status: Enrolling By Invitation → Unknown Status

▶ Show 3 earlier versions

  1. Jan 2021 — Mar 2022 [monthly]

    Enrolling By Invitation PHASE3

  2. May 2019 — Jan 2021 [monthly]

    Enrolling By Invitation PHASE3

  3. Nov 2018 — May 2019 [monthly]

    Enrolling By Invitation PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University of Southern California
Data source: University of Southern California

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations