deltatrials
Recruiting OBSERVATIONAL NCT03702309

Liquid Biopsy Evaluation and Repository Development at Princess Margaret (LIBERATE)

Sponsor: University Health Network, Toronto

Conditions BRCA1 Mutation BRCA2 Mutation Breast Cancer Cancer Colon Cancer Cowden Syndrome Head and Neck Cancer Kidney Cancer Leukemia Lung Cancer Lymphoma Lynch Syndrome Melanoma Meningioma Mutation Myeloma Ovarian Cancer Uterine Cancer
Updated 15 times since 2018 Last updated: Nov 25, 2025 Started: Aug 3, 2017 Primary completion: Jul 6, 2026 Completion: Jul 6, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This observational or N/A phase trial investigates BRCA1 Mutation and BRCA2 Mutation and is currently actively recruiting participants. University Health Network, Toronto leads this study, which shows 15 recorded versions since 2017 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Nov 2018 – ~Dec 2018 · 30 days · monthly snapshot~Dec 2018 – ~Feb 2019 · 2 months · monthly snapshot~Feb 2019 – ~Oct 2019 · 8 months · monthly snapshot~Oct 2019 – ~Nov 2020 · 13 months · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~May 2022 · 3 months · monthly snapshot~May 2022 – ~Jun 2023 · 13 months · monthly snapshot~Jun 2023 – ~Jan 2024 · 7 months · monthly snapshot~Jan 2024 – ~Jul 2024 · 6 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2025 · 15 months · monthly snapshot~Dec 2025 – present · 8 months · monthly snapshot

Change History

15 versions recorded

  1. Dec 2025 — Present [monthly]

    Recruiting

  2. Sep 2024 — Dec 2025 [monthly]

    Recruiting

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  4. Jan 2024 — Jul 2024 [monthly]

    Recruiting

  5. Jun 2023 — Jan 2024 [monthly]

    Recruiting

▶ Show 10 earlier versions

  1. May 2022 — Jun 2023 [monthly]

    Recruiting

    Status: Active Not Recruiting → Recruiting

  2. Feb 2022 — May 2022 [monthly]

    Active Not Recruiting

    Status: Recruiting → Active Not Recruiting

  3. Dec 2021 — Feb 2022 [monthly]

    Recruiting

  4. Jan 2021 — Dec 2021 [monthly]

    Recruiting

  5. Dec 2020 — Jan 2021 [monthly]

    Recruiting

  6. Nov 2020 — Dec 2020 [monthly]

    Recruiting

  7. Oct 2019 — Nov 2020 [monthly]

    Recruiting

  8. Feb 2019 — Oct 2019 [monthly]

    Recruiting

  9. Dec 2018 — Feb 2019 [monthly]

    Recruiting

  10. Nov 2018 — Dec 2018 [monthly]

    Recruiting

    First recorded

Aug 2017

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University Health Network, Toronto
Data source: University Health Network, Toronto

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations