deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT03702829

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

24 Month Open Label Study of the Tolerability and Efficacy of an Antisense Oligonucleotide (Inotersen) in Patients With Transthyretin (TTR) Amyloid Cardiomyopathy

Sponsor: Brigham and Women's Hospital

Conditions Amyloidosis
Interventions Inotersen
Updated 7 times since 2018 Last updated: Feb 18, 2026 Started: Feb 28, 2019 Primary completion: Dec 31, 2021 Completion: Jan 15, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

recruitment of new patients not possible during Covid 19 epidemic

A PHASE2 clinical study on Amyloidosis, this trial is terminated or withdrawn. The trial is conducted by Brigham and Women's Hospital and has accumulated 7 data snapshots since 2019. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Nov 2018 – ~Sep 2019 · 10 months · monthly snapshotNot Yet Recruiting~Sep 2019 – ~Jan 2021 · 16 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2023 · 25 months · monthly snapshotActive Not Recruiting~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshotUnknown~Feb 2026 – present · 6 months · monthly snapshotTerminated

Change History

7 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE2

    Status: UnknownTerminated

  2. Sep 2024 — Feb 2026 [monthly]

    Unknown PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2

    Status: Unknown StatusUnknown

  4. Feb 2023 — Jul 2024 [monthly]

    Unknown Status PHASE2

    Status: Active Not RecruitingUnknown Status

  5. Jan 2021 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 2 earlier versions
  1. Sep 2019 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  2. Nov 2018 — Sep 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Brigham and Women's Hospital
Data source: Brigham and Women's Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations