deltatrials
Active Not Recruiting PHASE3 INTERVENTIONAL 2-arm NCT03706690

A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients (PACIFIC-5)

A Phase III, Randomised,Double-Blind,Placebo-Controlled,Study of Durvalumab as Consolidation Therapy in Patients With Locally Advanced,Unresectable NSCLC, Who Have Not Progressed Following Definitive, Platinum-Based Chemoradiation Therapy

Sponsor: AstraZeneca

Conditions Carcinoma, Non-Small-Cell Lung
Interventions Durvalumab Placebo
Updated 53 times since 2018 Last updated: Feb 10, 2026 Started: Nov 27, 2018 Primary completion: Jun 23, 2024 Completion: Feb 26, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Carcinoma, Non-Small-Cell Lung, this trial is ongoing. The trial is conducted by AstraZeneca and has accumulated 53 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Sep 2020 · 3 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~May 2022 · 3 months · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~May 2023 · 3 months · monthly snapshot~May 2023 – ~Aug 2023 · 3 months · monthly snapshot~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshot~Nov 2023 – ~Jan 2024 · 2 months · monthly snapshot~Jan 2024 – ~Mar 2024 · 2 months · monthly snapshot~Mar 2024 – ~Jun 2024 · 3 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Mar 2025 · 3 months · monthly snapshot~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – ~Aug 2025 · 3 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Dec 2025 · 3 months · monthly snapshot~Dec 2025 – ~Mar 2026 · 3 months · monthly snapshot~Mar 2026 – present · 5 months · monthly snapshot

Change History

53 versions recorded

  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE3

  2. Dec 2025 — Mar 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  5. May 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE3

▶ Show 48 earlier versions

  1. Mar 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE3

  2. Dec 2024 — Mar 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  6. Mar 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE3

  7. Jan 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE3

  8. Nov 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE3

  9. Aug 2023 — Nov 2023 [monthly]

    Active Not Recruiting PHASE3

  10. May 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE3

  11. Feb 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE3

  12. Sep 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

  13. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

  14. May 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE3

    Status: Recruiting → Active Not Recruiting

  15. Feb 2022 — May 2022 [monthly]

    Recruiting PHASE3

  16. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  17. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  18. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  19. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  20. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  21. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  22. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  23. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

  24. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  25. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  26. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  27. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  28. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  29. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  30. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  31. Jun 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  32. May 2020 — Jun 2020 [monthly]

    Recruiting PHASE3

  33. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE3

  34. Mar 2020 — Apr 2020 [monthly]

    Recruiting PHASE3

  35. Feb 2020 — Mar 2020 [monthly]

    Recruiting PHASE3

  36. Jan 2020 — Feb 2020 [monthly]

    Recruiting PHASE3

  37. Dec 2019 — Jan 2020 [monthly]

    Recruiting PHASE3

  38. Nov 2019 — Dec 2019 [monthly]

    Recruiting PHASE3

  39. Oct 2019 — Nov 2019 [monthly]

    Recruiting PHASE3

  40. Sep 2019 — Oct 2019 [monthly]

    Recruiting PHASE3

  41. Aug 2019 — Sep 2019 [monthly]

    Recruiting PHASE3

  42. Jul 2019 — Aug 2019 [monthly]

    Recruiting PHASE3

  43. Jun 2019 — Jul 2019 [monthly]

    Recruiting PHASE3

  44. May 2019 — Jun 2019 [monthly]

    Recruiting PHASE3

  45. Apr 2019 — May 2019 [monthly]

    Recruiting PHASE3

  46. Mar 2019 — Apr 2019 [monthly]

    Recruiting PHASE3

  47. Jan 2019 — Mar 2019 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  48. Nov 2018 — Jan 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AstraZeneca
Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adana, Turkey (Türkiye) , Ankara, Turkey (Türkiye) , Bacolod, Philippines , Baguio City, Philippines , Bangalore, India , Beijing, China , Bengaluru, India , Bengbu, China , Bialystok, Poland , Cagayan de Oro, Philippines and 59 more locations