deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT03708315

BXCL501 for Agitation in Schizophrenia (DEX)

Safety and Efficacy of BXCL501, a Sublingual Film Delivery of Dexmedetomidine for the Treatment of Acute Agitation in Schizophrenia

Sponsor: Yale University

Updated 13 times since 2018 Last updated: Jul 18, 2025 Started: Mar 9, 2020 Primary completion: May 26, 2023 Completion: May 26, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Schizoaffective Disorder and Schizophrenia and is currently completed. Yale University leads this study, which shows 13 recorded versions since 2020 — indicating substantial longitudinal coverage. This study adds to the longitudinal dataset for psychiatric treatment development.

Status Flow

~Nov 2018 – ~Jan 2020 · 14 months · monthly snapshot~Jan 2020 – ~Apr 2020 · 3 months · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jan 2021 · 8 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Feb 2022 · 12 months · monthly snapshot~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshot~Sep 2022 – ~May 2023 · 8 months · monthly snapshot~May 2023 – ~Jun 2024 · 13 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshot~Aug 2025 – present · 11 months · monthly snapshot

Change History

13 versions recorded
  1. Aug 2025 — Present [monthly]

    Completed PHASE1

    Status: RecruitingCompleted · Phase: PHASE2PHASE1

  2. Sep 2024 — Aug 2025 [monthly]

    Recruiting PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

  4. Jun 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  5. May 2023 — Jun 2024 [monthly]

    Recruiting PHASE2

Show 8 earlier versions
  1. Sep 2022 — May 2023 [monthly]

    Recruiting PHASE2

  2. Feb 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  3. Feb 2021 — Feb 2022 [monthly]

    Recruiting PHASE2

    Status: Active Not RecruitingRecruiting

  4. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE2

  5. May 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  6. Apr 2020 — May 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Jan 2020 — Apr 2020 [monthly]

    Not Yet Recruiting PHASE2

  8. Nov 2018 — Jan 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Yale University
Data source: Yale University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations