deltatrials
Terminated PHASE1/PHASE2 INTERVENTIONAL 4-arm NCT03709082

Palbociclib in Estrogen Receptor Positive (ER+) Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

A Phase I/II Study of Palbociclib, Letrozole and T-DM1 in Trastuzumab Refractory Estrogen Receptor Positive (ER+) and HER2 Positive Metastatic Breast Cancer

Sponsor: Pfizer

Updated 7 times since 2018 Last updated: Mar 1, 2024 Started: Oct 15, 2018 Primary completion: Mar 12, 2020 Completion: Feb 3, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Low accrual

Listed as NCT03709082, this PHASE1/PHASE2 trial focuses on Breast Cancer Metastatic and HER2-positive Breast Cancer and remains terminated or withdrawn. Sponsored by Pfizer, it has been updated 7 times since 2018, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Nov 2018 – ~Dec 2019 · 13 months · monthly snapshotRecruiting~Dec 2019 – ~Dec 2020 · 12 months · monthly snapshotRecruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotActive Not Recruiting~Jan 2021 – ~Apr 2024 · 39 months · monthly snapshotActive Not Recruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

7 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Apr 2024 — Jul 2024 [monthly]

    Terminated PHASE1_PHASE2

    Status: Active Not RecruitingTerminated

  4. Jan 2021 — Apr 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  5. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

Show 2 earlier versions
  1. Dec 2019 — Dec 2020 [monthly]

    Recruiting PHASE1_PHASE2

  2. Nov 2018 — Dec 2019 [monthly]

    Recruiting PHASE1_PHASE2

    First recorded

Oct 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer
  • University of Kansas Medical Center
Data source: University of Kansas Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .