Completed PHASE1 INTERVENTIONAL 8-arm NCT03710434

AZD4635 Relative Bioavailability Study (Rel Bio)

A Phase I, Open-Label Study to Assess the Pharmacokinetics and Relative Bioavailability of AZD4635 in Non-Smoking Healthy Male Subjects, With the Option to Assess Food Effect, pH Effect and Absolute Bioavailability

Sponsor: AstraZeneca

Conditions Healthy Volunteers

Interventions AZD4635 50 mg nano-suspension (reference) AZD4635 solid oral formulation - fasted AZD4635 solid oral formulation - fed AZD4635 solid oral formulation variant 1 - fasted AZD4635 solid oral formulation variant 2 - fasted Lansoprazole and AZD4635 50 mg solid oral formulation [14C] AZD4635 IV microtracer - fasted

Updated 10 times since 2018 Last updated: May 5, 2020 Started: Nov 1, 2018 Primary completion: Apr 2, 2019 Completion: Apr 2, 2019

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Healthy Volunteers, this trial is completed. The trial is conducted by AstraZeneca and has accumulated 10 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

10 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE1
Jul 2024 — Sep 2024 [monthly]

Completed PHASE1
Jan 2021 — Jul 2024 [monthly]

Completed PHASE1
Jun 2020 — Jan 2021 [monthly]

Completed PHASE1
May 2019 — Jun 2020 [monthly]

Completed PHASE1

Status: Active Not Recruiting → Completed

▶ Show 5 earlier versions

Mar 2019 — May 2019 [monthly]

Active Not Recruiting PHASE1

Status: Recruiting → Active Not Recruiting
Feb 2019 — Mar 2019 [monthly]

Recruiting PHASE1
Jan 2019 — Feb 2019 [monthly]

Recruiting PHASE1
Dec 2018 — Jan 2019 [monthly]

Recruiting PHASE1

Status: Not Yet Recruiting → Recruiting
Nov 2018 — Dec 2018 [monthly]

Not Yet Recruiting PHASE1

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

AstraZeneca
Quotient Sciences

Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Ruddington, United Kingdom