deltatrials
Terminated PHASE2 INTERVENTIONAL 4-arm NCT03722966

Effectiveness of Combination Varenicline and Oral Nicotine Replacement Therapy (COMBO)

A Comparison of the Effectiveness of Combination Varenicline and Oral Nicotine Replacement Therapy Versus Varenicline Alone for Smoking Cessation: a Pilot Study

Sponsor: Pfizer

Updated 16 times since 2018 Last updated: Jan 10, 2024 Started: Jan 7, 2020 Primary completion: Feb 7, 2022 Completion: Feb 7, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Following the Chantix recall, Pfizer stopped providing medication for the study and and new study enrollments were discontinued.

Listed as NCT03722966, this PHASE2 trial focuses on Smoking Cessation and remains terminated or withdrawn. Sponsored by Pfizer, it has been updated 16 times since 2020, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Nov 2018 – ~Sep 2019 · 10 months · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Dec 2019 · 2 months · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~May 2020 · 4 months · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Mar 2022 · 4 months · monthly snapshot~Mar 2022 – ~Nov 2022 · 8 months · monthly snapshot~Nov 2022 – ~Mar 2024 · 16 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

16 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Mar 2024 — Jul 2024 [monthly]

    Terminated PHASE2

  4. Nov 2022 — Mar 2024 [monthly]

    Terminated PHASE2

  5. Mar 2022 — Nov 2022 [monthly]

    Terminated PHASE2

    Status: SuspendedTerminated

Show 11 earlier versions
  1. Nov 2021 — Mar 2022 [monthly]

    Suspended PHASE2

    Status: RecruitingSuspended

  2. Sep 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  3. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  4. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE2

  5. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Active Not RecruitingRecruiting

  6. May 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  7. Jan 2020 — May 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  8. Dec 2019 — Jan 2020 [monthly]

    Not Yet Recruiting PHASE2

  9. Oct 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE2

  10. Sep 2019 — Oct 2019 [monthly]

    Not Yet Recruiting PHASE2

  11. Nov 2018 — Sep 2019 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pfizer
  • University of Oklahoma
Data source: University of Oklahoma

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations