Completed PHASE2 INTERVENTIONAL 5-arm NCT03731364

Study of CA-008 (Vocacapsaicin) in Total Knee Arthroplasty

A Phase 2, Randomized, Double-blind, Placebo-Controlled Efficacy, Pharmacokinetics and Safety Study of CA-008 (Vocacapsaicin) in Subjects Undergoing Total Knee Arthroplasty

Sponsor: Concentric Analgesics

Conditions Postsurgical Pain

Interventions CA-008 Placebo

Updated 9 times since 2018 Last updated: Jan 25, 2022 Started: Oct 29, 2018 Primary completion: Apr 30, 2019 Completion: May 31, 2019

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Postsurgical Pain and is currently completed. Concentric Analgesics leads this study, which shows 9 recorded versions since 2018 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

9 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Mar 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Mar 2022 [monthly]

Completed PHASE2
Jul 2020 — Jan 2021 [monthly]

Completed PHASE2

▶ Show 4 earlier versions

Aug 2019 — Jul 2020 [monthly]

Completed PHASE2

Status: Active Not Recruiting → Completed
May 2019 — Aug 2019 [monthly]

Active Not Recruiting PHASE2

Status: Recruiting → Active Not Recruiting
Feb 2019 — May 2019 [monthly]

Recruiting PHASE2
Dec 2018 — Feb 2019 [monthly]

Recruiting PHASE2

First recorded

Oct 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Concentric Analgesics

Data source: Concentric Analgesics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Houston, United States