deltatrials
Active Not Recruiting NA INTERVENTIONAL 2-arm NCT03739372

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma (PNOC008)

A Pilot Trial Testing the Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan in Children and Young Adults With High Grade Glioma (Excluding Diffuse Intrinsic Pontine Glioma)

Sponsor: Pacific Pediatric Neuro-Oncology Consortium

Conditions Astrocytoma Cancer Glioblastoma Glioma Glioma of Brain Hemispheric Pediatric Brain Tumor Pediatric Cancer
Interventions Specialized tumor board recommendation
Updated 29 times since 2018 Last updated: Jul 8, 2025 Started: Nov 28, 2018 Primary completion: Dec 31, 2023 Completion: Jan 1, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Astrocytoma and Cancer, this trial is ongoing. The trial is conducted by Pacific Pediatric Neuro-Oncology Consortium and has accumulated 29 data snapshots since 2018. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Dec 2018 – ~Jun 2019 · 6 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Feb 2020 · 2 months · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~Aug 2020 · 4 months · monthly snapshot~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Oct 2021 · 4 months · monthly snapshot~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshot~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshot~Mar 2022 – ~Sep 2022 · 6 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Dec 2023 · 9 months · monthly snapshot~Dec 2023 – ~Mar 2024 · 3 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Aug 2025 · 5 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

29 versions recorded

  1. Sep 2025 — Present [monthly]

    Active Not Recruiting NA

  2. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting NA

  3. Mar 2025 — Aug 2025 [monthly]

    Active Not Recruiting NA

  4. Sep 2024 — Mar 2025 [monthly]

    Active Not Recruiting NA

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting NA

▶ Show 24 earlier versions

  1. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting NA

  2. Dec 2023 — Mar 2024 [monthly]

    Active Not Recruiting NA

  3. Mar 2023 — Dec 2023 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  4. Feb 2023 — Mar 2023 [monthly]

    Recruiting NA

  5. Sep 2022 — Feb 2023 [monthly]

    Recruiting NA

  6. Mar 2022 — Sep 2022 [monthly]

    Recruiting NA

  7. Jan 2022 — Mar 2022 [monthly]

    Recruiting NA

  8. Oct 2021 — Jan 2022 [monthly]

    Recruiting NA

  9. Jun 2021 — Oct 2021 [monthly]

    Recruiting NA

  10. May 2021 — Jun 2021 [monthly]

    Recruiting NA

  11. Apr 2021 — May 2021 [monthly]

    Recruiting NA

  12. Feb 2021 — Apr 2021 [monthly]

    Recruiting NA

  13. Jan 2021 — Feb 2021 [monthly]

    Recruiting NA

  14. Oct 2020 — Jan 2021 [monthly]

    Recruiting NA

  15. Aug 2020 — Oct 2020 [monthly]

    Recruiting NA

  16. Apr 2020 — Aug 2020 [monthly]

    Recruiting NA

  17. Mar 2020 — Apr 2020 [monthly]

    Recruiting NA

  18. Feb 2020 — Mar 2020 [monthly]

    Recruiting NA

  19. Dec 2019 — Feb 2020 [monthly]

    Recruiting NA

  20. Nov 2019 — Dec 2019 [monthly]

    Recruiting NA

  21. Aug 2019 — Nov 2019 [monthly]

    Recruiting NA

  22. Jul 2019 — Aug 2019 [monthly]

    Recruiting NA

  23. Jun 2019 — Jul 2019 [monthly]

    Recruiting NA

  24. Dec 2018 — Jun 2019 [monthly]

    Recruiting NA

    First recorded

Nov 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Pacific Pediatric Neuro-Oncology Consortium
  • The V Foundation for Cancer Research
  • University of California, San Francisco
Data source: University of California, San Francisco

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Baltimore, United States , Chicago, United States , Columbus, United States , Gainesville, United States , Minneapolis, United States , Philadelphia, United States , Salt Lake City, United States , San Diego, United States , San Francisco, United States , Seattle, United States and 2 more locations