Terminated PHASE3 INTERVENTIONAL 2-arm NCT03739476

Clinical Trial With Quetiapine Prophylaxis Postoperative Delirium in High Risk Surgical Patients

Controlled, Double-blind, Randomized Clinical Trial for Prophylaxis of Postoperative Delirium in High Risk Surgical Patients With Quetiapine

Sponsor: Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León

Conditions Postoperative Delirium

Interventions Placebo oral capsule Quetiapine 25 milligrams capsule

Updated 10 times since 2018 Last updated: May 21, 2025 Started: Feb 13, 2019 Primary completion: Apr 2, 2020 Completion: Jun 30, 2020

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Due to the crisis SARS-COV-2 pandemic: recruitment of patients for the trial is stopped, healthcare pressure generated, suspend the non-essential scheduled surgical activity and on June 30, 2020 medication expired, funding has been exhausted.

Other terminated trials from Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León

Corona Virus Infection · Phase PHASE4 · Nov 2021

See all terminations from Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León

This PHASE3 trial investigates Postoperative Delirium and is currently terminated or withdrawn. Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León leads this study, which shows 10 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

10 versions recorded

Jun 2025 — Present [monthly]

Terminated PHASE3
Sep 2024 — Jun 2025 [monthly]

Terminated PHASE3
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE3
Jul 2022 — Jul 2024 [monthly]

Terminated PHASE3
Dec 2021 — Jul 2022 [monthly]

Terminated PHASE3

▶ Show 5 earlier versions

Feb 2021 — Dec 2021 [monthly]

Terminated PHASE3

Status: Recruiting → Terminated
Jan 2021 — Feb 2021 [monthly]

Recruiting PHASE3
Jan 2020 — Jan 2021 [monthly]

Recruiting PHASE3
Jan 2019 — Jan 2020 [monthly]

Recruiting PHASE3

Status: Not Yet Recruiting → Recruiting
Dec 2018 — Jan 2019 [monthly]

Not Yet Recruiting PHASE3

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Grupo Español de Rehabilitación Multimodal
Instituto de Investigación Biomédica de Salamanca

Data source: Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Salamanca, Spain