Pyloroplasty Versus No Pyloroplasty in Patients Undergoing Esophagectomy
A Phase III Randomized Trial of Pyloroplasty Versus No Pyloroplasty in Patients Undergoing Esophagectomy
Sponsor: University of Pittsburgh
A observational or N/A phase clinical study on Esophagectomy, this trial is ongoing. The trial is conducted by University of Pittsburgh and has accumulated 14 data snapshots since 2018. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.
Study Description(click to expand)Patients selected for enrollment in this study will be adults (18-85 years of age) that have been scheduled for exploration, and possible esophagectomy. Prior to surgery, patients will be randomized to one of two groups. Group A will have a pyloroplasty performed as part of the esophagectomy procedure. Group B will not have a pyloroplasty performed. Postoperative patient outcomes will be assessed for 24 months.
Patients selected for enrollment in this study will be adults (18-85 years of age) that have been scheduled for exploration, and possible esophagectomy. Prior to surgery, patients will be randomized to one of two groups. Group A will have a pyloroplasty performed as part of the esophagectomy procedure. Group B will not have a pyloroplasty performed. Postoperative patient outcomes will be assessed for 24 months.
Status Flow
Change History
14 versions recorded-
Apr 16, 2026 — Present [daily]
Active Not Recruiting
Phase: NA → None
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Nov 2025 — Apr 2026 [monthly]
Active Not Recruiting NA
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May 2025 — Nov 2025 [monthly]
Active Not Recruiting NA
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Feb 2025 — May 2025 [monthly]
Active Not Recruiting NA
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Sep 2024 — Feb 2025 [monthly]
Active Not Recruiting NA
▶ Show 9 earlier versions
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Jul 2024 — Sep 2024 [monthly]
Active Not Recruiting NA
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Mar 2024 — Jul 2024 [monthly]
Active Not Recruiting NA
Status: Recruiting → Active Not Recruiting
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Feb 2023 — Mar 2024 [monthly]
Recruiting NA
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Feb 2022 — Feb 2023 [monthly]
Recruiting NA
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Jan 2021 — Feb 2022 [monthly]
Recruiting NA
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Nov 2020 — Jan 2021 [monthly]
Recruiting NA
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Nov 2019 — Nov 2020 [monthly]
Recruiting NA
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Mar 2019 — Nov 2019 [monthly]
Recruiting NA
Status: Not Yet Recruiting → Recruiting
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Dec 2018 — Mar 2019 [monthly]
Not Yet Recruiting NA
First recorded
Nov 2018
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
This research study is a phase III randomized trial to study the value of the addition of a pyloroplasty procedure versus no pyloroplasty procedure during the performance of esophagectomy. Pyloroplasty is a type of pyloric drainage procedure.
Contact Information
- University of Pittsburgh
For direct contact, visit the study record on ClinicalTrials.gov .