Completed OBSERVATIONAL NCT03758183

Cost Effectiveness of Prolotherapy Injections Prior to Total Knee Arthroplasty

Cost Effectiveness of Two-stage Algorithm (Prolotherapy Injections Prior to Total Knee Arthroplasty) in the Management of Advanced Stage Knee Osteoarthritis

Sponsor: Tokat State Hospital

Conditions Knee Osteoarthritis

Interventions total knee arthroplasty

Updated 5 times since 2018 Last updated: Nov 28, 2018 Started: Jan 1, 2016 Primary completion: Jan 1, 2017 Completion: Oct 24, 2018

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT03758183, this observational or N/A phase trial focuses on Knee Osteoarthritis and remains completed. Sponsored by Tokat State Hospital, it has been updated 5 times since 2016, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

5 versions recorded

Sep 2025 — Present [monthly]

Completed
Sep 2024 — Sep 2025 [monthly]

Completed
Jul 2024 — Sep 2024 [monthly]

Completed
Jan 2021 — Jul 2024 [monthly]

Completed
Dec 2018 — Jan 2021 [monthly]

Completed

First recorded

Jan 2016

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Tokat State Hospital

Data source: Tokat State Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Tokat Province, Turkey (Türkiye)