deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT03765541

Dexamethasone in Refractory or First Relapsed Acute Myeloid Leukemia (DEXAML-03)

Dexamethasone Plus Salvage Chemotherapy Versus Salvage Chemotherapy Alone in Patients With First Relapsed or Refractory Acute Myeloid Leukemia: a Randomized, Controlled, Open-label, Multicenter, Phase III Study

Sponsor: University Hospital, Toulouse

Updated 10 times since 2019 Last updated: Apr 7, 2025 Started: Jan 13, 2020 Primary completion: May 31, 2024 Completion: May 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Despite a recruitment target that was not met, we managed to achieve more than 50% of inclusions and 33% of deaths, enabling us to carry out an initial analysis of the primary endpoint

A PHASE3 clinical study on Relapsed or Refractory Acute Myeloid Leukemia, this trial is terminated or withdrawn. The trial is conducted by University Hospital, Toulouse and has accumulated 10 data snapshots since 2020. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2019 – ~May 2019 · 4 months · monthly snapshotNot Yet Recruiting~May 2019 – ~Dec 2019 · 7 months · monthly snapshotNot Yet Recruiting~Dec 2019 – ~Aug 2020 · 8 months · monthly snapshotNot Yet Recruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotRecruiting~Jan 2021 – ~Sep 2022 · 20 months · monthly snapshotRecruiting~Sep 2022 – ~Oct 2023 · 13 months · monthly snapshotRecruiting~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~May 2025 · 8 months · monthly snapshotRecruiting~May 2025 – present · 14 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. May 2025 — Present [monthly]

    Terminated PHASE3

    Status: RecruitingTerminated

  2. Sep 2024 — May 2025 [monthly]

    Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  4. Oct 2023 — Jul 2024 [monthly]

    Recruiting PHASE3

  5. Sep 2022 — Oct 2023 [monthly]

    Recruiting PHASE3

Show 5 earlier versions
  1. Jan 2021 — Sep 2022 [monthly]

    Recruiting PHASE3

  2. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  3. Dec 2019 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE3

  4. May 2019 — Dec 2019 [monthly]

    Not Yet Recruiting PHASE3

  5. Jan 2019 — May 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University Hospital, Toulouse
Data source: University Hospital, Toulouse

For direct contact, visit the study record on ClinicalTrials.gov .