deltatrials
Unknown PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT03772353

Pyrotinib, Dalpiciclib(SHR6390) and Endocrine Therapy in Subjects With Dual-receptor Positive(ER+/HER2+) Advanced Breast Cancer (PLEASURABLE)

Pyrotinib, Dalpiciclib(SHR6390) and Endocrine Therapy in Subjects With Dual-receptor Positive(ER+/HER2+) Advanced Breast Cancer: a Multi-center Phase Ib/II Study

Sponsor: Fudan University

Conditions Breast Cancer
Updated 11 times since 2019 Last updated: Mar 5, 2023 Started: May 12, 2019 Primary completion: Jun 10, 2023 Completion: Dec 10, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Breast Cancer and is currently ongoing. Fudan University leads this study, which shows 11 recorded versions since 2019 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2019 – ~Mar 2019 · 59 days · monthly snapshotNot Yet Recruiting~Mar 2019 – ~Jan 2020 · 10 months · monthly snapshotRecruiting~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshotRecruiting~Jan 2021 – ~May 2021 · 4 months · monthly snapshotRecruiting~May 2021 – ~Jun 2021 · 31 days · monthly snapshotRecruiting~Jun 2021 – ~Mar 2022 · 9 months · monthly snapshotRecruiting~Mar 2022 – ~Apr 2023 · 13 months · monthly snapshotRecruiting~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Jan 2026 · 16 months · monthly snapshotActive Not Recruiting~Jan 2026 – present · 7 months · monthly snapshotUnknown

Change History

11 versions recorded
  1. Jan 2026 — Present [monthly]

    Unknown PHASE1/PHASE2

    Status: Active Not RecruitingUnknown

  2. Sep 2024 — Jan 2026 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Apr 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  5. Mar 2022 — Apr 2023 [monthly]

    Recruiting PHASE1_PHASE2

Show 6 earlier versions
  1. Jun 2021 — Mar 2022 [monthly]

    Recruiting PHASE1_PHASE2

  2. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE1_PHASE2

  3. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE1_PHASE2

  4. Jan 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

  5. Mar 2019 — Jan 2020 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Jan 2019 — Mar 2019 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Fudan University
  • Jiangsu HengRui Medicine Co., Ltd.
Data source: Fudan University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations