deltatrials
Completed NA INTERVENTIONAL 2-arm NCT03803748

A Non-inferiority Study of Eyestil® Plus Multidose Versus Vismed Multi® (047/SI)

A Prospective Multicenter, Comparative, Randomized, Double-blind, Non-inferiority Study of Eyestil® Plus Multidose Versus Vismed Multi® in Patients With Moderate to Severe Dry Eye Syndrome

Sponsor: SIFI SpA

Interventions Eyestil Plus®
Updated 10 times since 2019 Last updated: Dec 22, 2022 Started: Jul 17, 2019 Primary completion: May 2, 2022 Completion: Aug 31, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Dry Eye Syndromes and is currently completed. SIFI SpA leads this study, which shows 10 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Feb 2019 – ~Dec 2019 · 10 months · monthly snapshotNot Yet Recruiting~Dec 2019 – ~Jun 2020 · 6 months · monthly snapshotRecruiting~Jun 2020 – ~Jan 2021 · 7 months · monthly snapshotRecruiting~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshotRecruiting~Apr 2021 – ~Jun 2022 · 14 months · monthly snapshotRecruiting~Jun 2022 – ~Jan 2023 · 7 months · monthly snapshotActive Not Recruiting~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed NA

  2. Sep 2024 — Sep 2025 [monthly]

    Completed NA

  3. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  4. Jan 2023 — Jul 2024 [monthly]

    Completed NA

    Status: Active Not RecruitingCompleted

  5. Jun 2022 — Jan 2023 [monthly]

    Active Not Recruiting NA

    Status: RecruitingActive Not Recruiting

Show 5 earlier versions
  1. Apr 2021 — Jun 2022 [monthly]

    Recruiting NA

  2. Jan 2021 — Apr 2021 [monthly]

    Recruiting NA

  3. Jun 2020 — Jan 2021 [monthly]

    Recruiting NA

  4. Dec 2019 — Jun 2020 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  5. Feb 2019 — Dec 2019 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • SIFI SpA
Data source: SIFI SpA

For direct contact, visit the study record on ClinicalTrials.gov .