deltatrials
Recruiting PHASE1 INTERVENTIONAL 1-arm NCT03826992

Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

A Phase I Study of Venetoclax Combined With Vyxeos (CPX-351) for Children, Adolescents and Young Adults With Relapsed or Refractory Acute Leukemia

Sponsor: Children's Hospital Medical Center, Cincinnati

Conditions Leukemia
Updated 16 times since 2019 Last updated: Feb 16, 2026 Started: Dec 27, 2018 Primary completion: Jan 31, 2027 Completion: Jan 31, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Leukemia and is currently actively recruiting participants. Children's Hospital Medical Center, Cincinnati leads this study, which shows 16 recorded versions since 2018 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Mar 2019 – ~Nov 2019 · 8 months · monthly snapshot~Nov 2019 – ~May 2020 · 6 months · monthly snapshot~May 2020 – ~Jul 2020 · 2 months · monthly snapshot~Jul 2020 – ~Dec 2020 · 5 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshot~Sep 2022 – ~May 2023 · 8 months · monthly snapshot~May 2023 – ~Feb 2024 · 9 months · monthly snapshot~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Feb 2026 · 8 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

16 versions recorded
  1. Feb 2026 — Present [monthly]

    Recruiting PHASE1

  2. Jun 2025 — Feb 2026 [monthly]

    Recruiting PHASE1

  3. Apr 2025 — Jun 2025 [monthly]

    Recruiting PHASE1

  4. Sep 2024 — Apr 2025 [monthly]

    Recruiting PHASE1

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

Show 11 earlier versions
  1. Feb 2024 — Jul 2024 [monthly]

    Recruiting PHASE1

  2. May 2023 — Feb 2024 [monthly]

    Recruiting PHASE1

    Status: SuspendedRecruiting

  3. Sep 2022 — May 2023 [monthly]

    Suspended PHASE1

  4. Feb 2022 — Sep 2022 [monthly]

    Suspended PHASE1

    Status: RecruitingSuspended

  5. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE1

  6. Jan 2021 — Jan 2022 [monthly]

    Recruiting PHASE1

  7. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1

  8. Jul 2020 — Dec 2020 [monthly]

    Recruiting PHASE1

  9. May 2020 — Jul 2020 [monthly]

    Recruiting PHASE1

  10. Nov 2019 — May 2020 [monthly]

    Recruiting PHASE1

  11. Mar 2019 — Nov 2019 [monthly]

    Recruiting PHASE1

    First recorded

Dec 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Hospital Medical Center, Cincinnati
Data source: Children's Hospital Medical Center, Cincinnati

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations