deltatrials
Completed PHASE4 INTERVENTIONAL 1-arm NCT03840291

Resolution of Thrombi in Left Atrial Appendage With Edoxaban (REFLEX)

Sponsor: Daiichi Sankyo Korea Co., Ltd., a Daiichi Sankyo Company

Conditions Atrial Fibrillation Left Atrial Appendage Thrombosis
Interventions Edoxaban
Updated 8 times since 2019 Last updated: Aug 16, 2024 Started: May 19, 2019 Primary completion: Oct 30, 2023 Completion: Aug 1, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Atrial Fibrillation and Left Atrial Appendage Thrombosis and is currently completed. Daiichi Sankyo Korea Co., Ltd., a Daiichi Sankyo Company leads this study, which shows 8 recorded versions since 2019 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

~Mar 2019 – ~Jul 2020 · 16 months · monthly snapshotNot Yet Recruiting~Jul 2020 – ~Jan 2021 · 6 months · monthly snapshotRecruiting~Jan 2021 – ~Apr 2022 · 15 months · monthly snapshotRecruiting~Apr 2022 – ~Jun 2023 · 14 months · monthly snapshotRecruiting~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

8 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

    Status: Recruiting → Completed

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE4

  4. Jun 2023 — Jul 2024 [monthly]

    Recruiting PHASE4

  5. Apr 2022 — Jun 2023 [monthly]

    Recruiting PHASE4

▶ Show 3 earlier versions

  1. Jan 2021 — Apr 2022 [monthly]

    Recruiting PHASE4

  2. Jul 2020 — Jan 2021 [monthly]

    Recruiting PHASE4

    Status: Not Yet Recruiting → Recruiting

  3. Mar 2019 — Jul 2020 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Daiichi Sankyo Korea Co., Ltd., a Daiichi Sankyo Company
  • Keimyung University Dongsan Medical Center
Data source: Keimyung University Dongsan Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations