deltatrials
Recruiting NA INTERVENTIONAL 2-arm NCT03860883

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (MelMarT-II)

Melanoma Margins Trial-II - A Phase III, Multi-centre Randomised Controlled Trial Investigating 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (02.18 MelMarT-II)

Sponsor: Canadian Cancer Trials Group

Conditions Cutaneous Melanoma, Stage II
Interventions Wide Local Excision = 1cm Margin Wide Local Excision = 2cm Margin
Updated 37 times since 2019 Last updated: Nov 25, 2024 Started: Dec 17, 2019 Primary completion: Dec 31, 2029 Completion: Dec 31, 2034
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Cutaneous Melanoma, Stage II and is currently actively recruiting participants. Canadian Cancer Trials Group leads this study, which shows 37 recorded versions since 2019 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Apr 2019 – ~Aug 2019 · 4 months · monthly snapshot~Aug 2019 – ~Jan 2020 · 5 months · monthly snapshot~Jan 2020 – ~Jul 2020 · 6 months · monthly snapshot~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshot~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Feb 2023 · 2 months · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~Aug 2023 · 4 months · monthly snapshot~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshot~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Sep 2025 · 9 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

37 versions recorded

  1. Sep 2025 — Present [monthly]

    Recruiting NA

  2. Dec 2024 — Sep 2025 [monthly]

    Recruiting NA

    Phase: PHASE3 → NA

  3. Sep 2024 — Dec 2024 [monthly]

    Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  5. Nov 2023 — Jul 2024 [monthly]

    Recruiting PHASE3

▶ Show 32 earlier versions

  1. Aug 2023 — Nov 2023 [monthly]

    Recruiting PHASE3

  2. Apr 2023 — Aug 2023 [monthly]

    Recruiting PHASE3

  3. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE3

  4. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

  5. Dec 2022 — Feb 2023 [monthly]

    Recruiting PHASE3

  6. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  7. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  8. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  9. May 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  10. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

  11. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  12. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE3

  13. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  14. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  15. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  16. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  17. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  18. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  19. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  20. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

  21. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  22. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  23. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE3

  24. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

  25. Nov 2020 — Dec 2020 [monthly]

    Recruiting PHASE3

  26. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE3

  27. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE3

  28. Aug 2020 — Sep 2020 [monthly]

    Recruiting PHASE3

  29. Jul 2020 — Aug 2020 [monthly]

    Recruiting PHASE3

  30. Jan 2020 — Jul 2020 [monthly]

    Recruiting PHASE3

    Status: Not Yet Recruiting → Recruiting

  31. Aug 2019 — Jan 2020 [monthly]

    Not Yet Recruiting PHASE3

  32. Apr 2019 — Aug 2019 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Canadian Cancer Trials Group
  • Cancer Trials Ireland
  • Melanoma and Skin Cancer Trials Limited
  • Norfolk and Norwich University Hospitals NHS Foundation Trust
  • Zuyderland Medical Centre
Data source: Melanoma and Skin Cancer Trials Limited

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adelaide, Australia , Albuquerque, United States , Allentown, United States , Almere Stad, Netherlands , Ann Arbor, United States , Atlanta, United States , Auckland, New Zealand , Aventura, United States , Avon, United States , Baltimore, United States and 143 more locations