deltatrials
Recruiting NA INTERVENTIONAL 3-arm NCT03870672

rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke (rTMS+CCFES)

Contralaterally Controlled FES Combined With Brain Stimulation for Severe Upper Limb Hemiplegia

Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions Cerebrovascular Accident (CVA) Hemiparesis Hemiplegia Stroke
Interventions Contralaterally Controlled Functional Electrical Stimulation Conventional rTMS approach New rTMS approach Sham rTMS approach
Updated 15 times since 2019 Last updated: Aug 28, 2025 Started: May 14, 2019 Primary completion: Dec 31, 2025 Completion: Apr 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Cerebrovascular Accident (CVA) and Hemiparesis and is currently actively recruiting participants. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) leads this study, which shows 15 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Feb 2020 · 7 months · monthly snapshot~Feb 2020 – ~May 2020 · 3 months · monthly snapshot~May 2020 – ~Aug 2020 · 3 months · monthly snapshot~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Dec 2021 · 9 months · monthly snapshot~Dec 2021 – ~Apr 2022 · 4 months · monthly snapshot~Apr 2022 – ~Mar 2023 · 11 months · monthly snapshot~Mar 2023 – ~Mar 2024 · 12 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

15 versions recorded

  1. Oct 2025 — Present [monthly]

    Recruiting NA

  2. Sep 2024 — Oct 2025 [monthly]

    Recruiting NA

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  4. Mar 2024 — Jul 2024 [monthly]

    Recruiting NA

  5. Mar 2023 — Mar 2024 [monthly]

    Recruiting NA

▶ Show 10 earlier versions

  1. Apr 2022 — Mar 2023 [monthly]

    Recruiting NA

  2. Dec 2021 — Apr 2022 [monthly]

    Recruiting NA

  3. Mar 2021 — Dec 2021 [monthly]

    Recruiting NA

  4. Jan 2021 — Mar 2021 [monthly]

    Recruiting NA

  5. Aug 2020 — Jan 2021 [monthly]

    Recruiting NA

    Status: Active Not Recruiting → Recruiting

  6. May 2020 — Aug 2020 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

  7. Feb 2020 — May 2020 [monthly]

    Recruiting NA

  8. Jul 2019 — Feb 2020 [monthly]

    Recruiting NA

  9. Jun 2019 — Jul 2019 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  10. Apr 2019 — Jun 2019 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  • The Cleveland Clinic
Data source: The Cleveland Clinic

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations