deltatrials
Terminated NA INTERVENTIONAL 2-arm NCT03881007

A Trial to Compare Antibacterial vs. Placebo Mouthwash to Reduce the Incidence of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men (MSM) Taking HIV Pre-Exposure Prophylaxis (PrEP) (PReGo)

A Double-blind Single Center, Crossover, Randomized Controlled Trial of Antibacterial vs. Placebo Mouthwash to Reduce the Incidence of Gonorrhea/Chlamydia/Syphilis in MSM Taking HIV Pre-exposure Prophylaxis (PrEP)

Sponsor: Institute of Tropical Medicine, Belgium

Conditions Sexually Transmitted Diseases
Interventions Mouthwash with LCM Mouthwash with placebo
Updated 13 times since 2019 Last updated: Apr 12, 2021 Started: Apr 3, 2019 Primary completion: Jun 15, 2020 Completion: Jun 15, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

An interim analysis, planned because of the influence of the COVID-lockdown, showed the LCM mouthwash did not affect the incidence of Ng, Ct and syphilis.

Other terminated trials from Institute of Tropical Medicine, Belgium

See all terminations from Institute of Tropical Medicine, Belgium

This NA trial investigates Sexually Transmitted Diseases and is currently terminated or withdrawn. Institute of Tropical Medicine, Belgium leads this study, which shows 13 recorded versions since 2019 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Nov 2019 · 6 months · monthly snapshot~Nov 2019 – ~Aug 2020 · 9 months · monthly snapshot~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Dec 2021 · 6 months · monthly snapshot~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – present · 22 months · monthly snapshot

Change History

13 versions recorded

  1. Sep 2024 — Present [monthly]

    Terminated NA

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated NA

  3. Jan 2023 — Jul 2024 [monthly]

    Terminated NA

  4. Dec 2022 — Jan 2023 [monthly]

    Terminated NA

  5. Dec 2021 — Dec 2022 [monthly]

    Terminated NA

▶ Show 8 earlier versions

  1. Jun 2021 — Dec 2021 [monthly]

    Terminated NA

  2. May 2021 — Jun 2021 [monthly]

    Terminated NA

  3. Jan 2021 — May 2021 [monthly]

    Terminated NA

  4. Nov 2020 — Jan 2021 [monthly]

    Terminated NA

  5. Aug 2020 — Nov 2020 [monthly]

    Terminated NA

    Status: Recruiting → Terminated

  6. Nov 2019 — Aug 2020 [monthly]

    Recruiting NA

  7. May 2019 — Nov 2019 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  8. Apr 2019 — May 2019 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Institute of Tropical Medicine, Belgium
Data source: Institute of Tropical Medicine, Belgium

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations