AScalate: Treat-to-target in Axial Spondyloarthritis (AScalate)
A Randomized, Open Label Multicenter Trial to Investigate the Efficacy of a Treat-to-target (T2T) Treatment Strategy With Secukinumab (AIN457) as a First-line Biologic Compared to a Standard-of-care (SOC) Treatment Over 36 Weeks in Patients With Active Axial Spondyloarthritis (axSpA)
Sponsor: Novartis Pharmaceuticals
A PHASE3 clinical study on Axial Spondyloarthritis, this trial is completed. The trial is conducted by Novartis Pharmaceuticals and has accumulated 17 data snapshots since 2019. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.
Status Flow
Change History
17 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE3
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May 2025 — Sep 2025 [monthly]
Completed PHASE3
-
Sep 2024 — May 2025 [monthly]
Completed PHASE3
-
Jul 2024 — Sep 2024 [monthly]
Completed PHASE3
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Aug 2023 — Jul 2024 [monthly]
Completed PHASE3
▶ Show 12 earlier versions
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Feb 2023 — Aug 2023 [monthly]
Completed PHASE3
Status: Active Not Recruiting → Completed
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Feb 2022 — Feb 2023 [monthly]
Active Not Recruiting PHASE3
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Jan 2022 — Feb 2022 [monthly]
Active Not Recruiting PHASE3
Status: Recruiting → Active Not Recruiting
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Sep 2021 — Jan 2022 [monthly]
Recruiting PHASE3
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Apr 2021 — Sep 2021 [monthly]
Recruiting PHASE3
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Jan 2021 — Apr 2021 [monthly]
Recruiting PHASE3
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Aug 2020 — Jan 2021 [monthly]
Recruiting PHASE3
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Apr 2020 — Aug 2020 [monthly]
Recruiting PHASE3
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Mar 2020 — Apr 2020 [monthly]
Recruiting PHASE3
-
Sep 2019 — Mar 2020 [monthly]
Recruiting PHASE3
Status: Not Yet Recruiting → Recruiting
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Jul 2019 — Sep 2019 [monthly]
Not Yet Recruiting PHASE3
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May 2019 — Jul 2019 [monthly]
Not Yet Recruiting PHASE3
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- Novartis Pharmaceuticals
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Bad Doberan, Germany , Bad Pyrmont, Germany , Berlin, Germany , Bonn, Germany , Caluire-et-Cuire, France , Chambray-lès-Tours, France , Chemnitz, Germany , Cologne, Germany , Cottbus, Germany , Dresden, Germany and 28 more locations